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Stock Market & Financial Investment News

News Breaks
March 18, 2014
10:54 EDTUQM, NDAQ, RGP, RNAHigh option volume stocks: UQM NDAQ RSX RGP RNA
News For UQM;NDAQ;RGP;RNA From The Last 14 Days
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October 29, 2014
05:20 EDTNDAQNASDAQ, Shenzhen Stock Exchange sign MOU
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October 28, 2014
07:38 EDTRGPRegency Energy Partners ups cash distribution by 7% to 50.25c
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October 27, 2014
16:36 EDTRNAOn The Fly: Closing Wrap
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12:30 EDTRNASarepta dives after FDA requests additional data on DMD drug
Shares of drug maker Sarepta (SRPT) are plunging after the FDA said the company would have to submit more data on its Duchenne muscular dystrophy, or DMD, drug before the agency would consider approving the treatment. WHAT'S NEW: The FDA informed Sarepta that it would have to submit additional data on its DMD drug, eteplirsen, before filling an application for FDA approval of the drug, Sarepta reported this morning. The FDA wants several additional data points, including four more weeks of data on 12 patients taking eteplirsen and three month data on 12-24 additional patients. The agency also requested MRI data on patients from a recent study conducted by an independent academic group. After reviewing the agency's requests, Sarepta said it expected to file a new application for approval of eteplirsen in the middle of next year. ANALYST REACTION: In a note to investors earlier today, Piper Jaffray analyst Edward Tenthoff wrote that the FDA is concerned about quality control issues involving the company's staining and analysis of dystrohpin, a protein that boosts muscle strength. DMD is triggered by errors in the gene that governs dystrohpin, and Sarepta has used dystrophin production levels as a primary endpoint for the evaluation of eteplirsen. The earliest that the drug could be approved by the FDA is 2016, wrote the analyst, who slashed his price target on the shares to $21 from $37. The FDA was not convinced of Sarepta's contention that dystrophin was an appropriate way to measure eteplirsen's effectiveness, Roth Capital contended. The firm does not expect Sarepta's drug to be approved until the first quarter of 2016 at the earliest. Roth says that its Buy rating and $34 price target on the name are under review. WHAT'S NOTABLE: Shares of Prosensa (RNA), which has also developed a DMD treatment, are climbing. Prosensa is due to file for FDA approval of its drug by the end of the year. According to Roth Capital, Prosensa has not relied on dystrophin levels to prove the effectiveness of its treatment. PRICE ACTION: In early afternoon trading, Sarepta tumbled 35% to $15.39, while Prosensa climbed 6% to $12.73.
12:27 EDTRNAOn The Fly: Midday Wrap
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09:14 EDTRNAOn The Fly: Pre-market Movers
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09:02 EDTRNAProsensa may benefit most from Sarepta news, says Roth Capital
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08:50 EDTRNAProsensa up 16% after FDA requires additional data from Sarepta
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October 24, 2014
08:08 EDTNDAQNASDAQ says U.S. equity volumes so far in October up 30% from prior year
Comment from NASDAQ's Q3 earnings conference call.
07:43 EDTNDAQNASDAQ reports U.S. IPO win rate 61% year-to-date
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07:06 EDTNDAQNASDAQ lowers non-GAAP operating expense guidance
NASDAQ lowered non-GAAP operating expense guidance to $1.205B-$1.225B, down from the prior $1.22B-$1.25B. Included in this non-GAAP operating expense guidance is an expected $30M-$35M in GIFT new initiative spending, down from a prior $30M-$40M estimate, and $1.175B-$1.19B in core non-GAAP operating expense, down from $1.19B-$1,21B.
07:04 EDTNDAQNASDAQ boosts stock repurchase authorization by $500M
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07:04 EDTNDAQNASDAQ reports Q3 EPS 73c, consensus 70c
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October 23, 2014
15:39 EDTNDAQNotable companies reporting before tomorrow's open
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10:01 EDTRGPOn The Fly: Analyst Downgrade Summary
Today's noteworthy downgrades include: 3D Systems (DDD) downgraded to Hold from Buy at Brean Capital... Angie's List (ANGI) downgraded to Hold from Buy at Needham... Avalon Rare Metals (AVL) downgraded to Neutral from Buy at Citigroup... Axiall (AXLL) downgraded at Cowen... BB&T (BBT) downgraded to Neutral from Buy at Goldman... Boeing (BA) downgraded at Credit Suisse... Boulder Brands (BDBD) downgraded to Hold from Buy at Canaccord... Citrix (CTXS) downgraded to Hold from Buy at Drexel Hamilton... ClickSoftware (CKSW) downgraded to Hold from Buy at Lake Street... DTS, Inc. (DTSI) downgraded to Underweight from Neutral at JPMorgan... GulfMark Offshore (GLF) downgraded to Market Perform from Outperform at Cowen... Home Loan Servicing (HLSS) downgraded to Neutral from Buy at Compass Point... ICON plc (ICLR) downgraded to Equal Weight from Overweight at First Analysis... IPC The Hospitalist Co. (IPCM) downgraded to Market Perform at Wells Fargo... Melco Crown (MPEL) downgraded to Neutral from Buy at Nomura... Mercer (MERC) downgraded at Credit Suisse... ONEOK Partners (OKS) downgraded to Neutral from Buy at BofA/Merrill... Owens Corning (OC) downgraded to Neutral from Overweight at JPMorgan... Regency Energy Partners (RGP) downgraded to Neutral from Buy at BofA/Merrill... The Medicines Co. (MDCO) downgraded to Neutral from Buy at BofA/Merrill... Tupperware Brands (TUP) downgraded to Neutral from Overweight at JPMorgan... Union Bankshares (UBSH) downgraded at RW Baird... VOC Energy Trust (VOC) downgraded at RBC Capital... Yelp (YELP) downgraded to Hold from Buy at Stifel.
06:47 EDTRGPRegency Energy Partners downgraded to Neutral from Buy at BofA/Merrill
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October 20, 2014
06:50 EDTRNAProsensa upgraded to Overweight from Underweight at JPMorgan
JPMorgan upgraded Prosensa two notches to Overweight citing a favorable risk/reward around the potential approval of Drisapersen for Duchenne muscular dystrophy. The firm believes regulatory risk for the drug has been significantly reduced in both the U.S. and Europe. JPMorgan raised its price target for shares to $18 from $4.40.

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