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News Breaks
June 1, 2014
14:24 EDTJNJ, TKPYYVelcade-based therapy 'significantly' improved progression-free survival
Millennium: The Takeda Oncology Company (TKPYY) announced results from the primary analysis of an international, randomized Phase 3 study that showed treatment with a VELCADE, bortezomib-based combination therapy demonstrated a 59% relative improvement in the study’s primary endpoint of progression-free survival among previously untreated patients with mantle cell lymphoma, MCL, compared to treatment with a standard therapy. These data were presented today at the annual meeting of the American Society of Clinical Oncology, ASCO. After a median follow up of 40 months, median overall survival, OS, a key secondary endpoint, had not been reached for patients who received the VELCADE-based therapy, while a median OS of 56.3 months was observed in patients treated with the standard regimen. Overall, among patients receiving VcR-CAP compared to R-CHOP, serious adverse events, SAEs, were reported in 38% vs. 30% of patients, and grade =3 adverse events were reported in 93% vs. 85% of patients. “The 59% relative improvement in progression-free survival, along with the trend suggesting improved OS with the VELCADE-based regimen, has the potential to represent a significant advance in the frontline treatment of mantle cell lymphoma for some patients,” said Michael Vasconcelles, MD, Global Head, Takeda Oncology Therapeutic Area Unit. “Patients with relapsed MCL have benefited from access to VELCADE therapy since 2006. We look forward to working with regulatory authorities to bring this new information to physicians and patients in the near future.” VELCADE is co-developed by Millennium/Takeda and Janssen Pharmaceutical Companies (JNJ).
News For TKPYY;JNJ From The Last 14 Days
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February 26, 2015
08:03 EDTJNJJohnson & Johnson forms new health and wellness platform
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06:52 EDTJNJPharmacyclics downgraded to Hold from Buy at WallachBeth
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February 25, 2015
14:47 EDTJNJPharmacyclics could fetch as much as $19B in sale, FT says
Pharmacyclics (PCYC) is considering a sale that could fetch as much as $19B, reported Financial Times, citing people familiar with the matter who said Johnson & Johnson (JNJ) is exploring a potential deal for the company. The Fly notes that Bloomberg had a similar report, but its report said Pharmacyclics could fetch $17B-$18B in a sale. Reference Link
14:10 EDTJNJPharmacyclics downgraded to Hold on lack of upside at Deutsche Bank
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12:54 EDTJNJPharmacyclics exploring options including sale, Bloomberg reports
According to sources, Pharmacyclics (PCYC), which develops cancer treatments, is currently exploring options, Bloomberg reports. One option may include a sale of the company, and the sources say Johnson & Johnson (JNJ) and Novartis (NVS) have expressed interest in the company. Pharmacyclics could fetch $17B-$18B in a sale, the sources add. Reference Link
12:53 EDTJNJPharmacyclics weighing sale to U.S. drugmaker, Bloomberg reports
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February 23, 2015
12:53 EDTTKPYYAnalysts debate potential for competing Salix takeover bid
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February 22, 2015
12:51 EDTJNJJ&J considers Cordis sale with Cardinal the leading suitor, Bloomberg says
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February 20, 2015
17:31 EDTJNJJ&J considering sale of Cordis with Cardinal the leading suitor, Bloomberg says
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16:03 EDTJNJOptions Update; February 20, 2015
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09:38 EDTJNJActive equity options trading on open
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07:23 EDTJNJAbbVie replaces Pfizer as top global pharma pick at Jefferies
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February 18, 2015
16:46 EDTJNJOn The Fly: Closing Wrap
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12:36 EDTJNJAnalysts applaud cheaper than expected Boston Scientific settlement
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12:31 EDTJNJOn The Fly: Midday Wrap
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07:41 EDTJNJSettlement 'a big win' for Boston Scientific, says Bernstein
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07:12 EDTJNJBoston Scientific settlement should remove overhang, says Stifel
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07:09 EDTJNJBoston Scientific payment to J&J well below expectations, says Piper Jaffray
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February 17, 2015
16:29 EDTJNJ Boston Scientific announces settltement of merger agreement lawsuit
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07:04 EDTJNJGTx names Robert Wills as executive chairman
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