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January 21, 2014
07:06 EDTTBIOTransgenomic Inc announces issuance of U.S. patent for ICE COLD-PCR
Transgenomic announced that the U.S. Patent and Trademark Office has issued a new patent related to its licensed ICE COLD-PCR technology. The patent, titled “Full cold-PCR enrichment with reference blocking sequence”, was assigned U.S. Patent No. 8,623,603 and is set to expire in 2031. The new U.S. patent extends the scope and longevity of the COLD-PCR intellectual property portfolio. The '603 patent covers ICE COLD-PCR methods for enriching low abundance alleles in nucleic acid samples. It is directed in particular to the use of an excess amount of reference blocking sequence in an amplification reaction mixture in order to improve the enrichment efficiency, and reduce cycle time, of full COLD-PCR.
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October 30, 2014
07:06 EDTTBIOTransgenomic, University of Melbourne announce collaboration
Transgenomic announced a research agreement with the University of Melbourne to conduct additional clinical validation studies of its Multiplexed ICE COLD-PCRTM technology. The new study will be conducted using DNA isolated from pre-treatment tumor biopsies from patients enrolled in clinical trials. It aims to determine the prevalence and clinical significance of ultra-low frequency mutations that would otherwise go undetected by NGS or Sanger sequencing-based methodologies. In the next phase of the project, Transgenomic expects to conduct further studies with University of Melbourne researchers to validate the use of MX-ICP to accurately detect tumor mutations using blood or plasma. Transgenomic’s MX ICE COLD-PCR technology is exclusively licensed from the Dana-Farber Cancer Institute.
07:04 EDTTBIOTransgenomic Inc reports Q3 EPS (5c), may not compare to one estimate (58c)
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October 20, 2014
07:10 EDTTBIOAmerican Society of Human Genetics to hold annual meeting
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