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July 17, 2014
13:34 EDTSHPGShire reports results from Vyvanse vs. Concerta studies in adolescents with ADHD
Shire announced top-line results from two Phase 4 efficacy and safety studies of Vyvanse compared with Concerta with a placebo reference arm in adolescents aged 13-17 diagnosed with Attention-Deficit/Hyperactivity Disorder. In SPD489-406, the forced-dose titration study, Vyvanse was found to be statistically superior to Concerta on the primary efficacy analysis with mean reductions on the ADHD RS-IV total score of 25.4 and 22.1 points, respectively. In SPD489-405, the dose optimization study, neither Vyvanse nor Concerta was found to be statistically superior to the other on the primary efficacy analysis, with a larger mean improvement found for Vyvanse than Concerta. The primary efficacy endpoint for both studies was defined as the change from baseline in ADHD-RS-IV total score at Week 6 and Week 8, respectively. In both studies, the types of adverse events appear to be generally consistent with the known safety profile for Vyvanse established in studies of adolescents with ADHD. Shire plans to submit the efficacy and safety data from the two studies for presentation at a future scientific congress.
News For SHPG From The Last 14 Days
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July 23, 2014
06:01 EDTSHPGStocks with implied volatility below IV index mean; INTC SHPG
Stocks with implied volatility below IV index mean; Intel (INTC) 18, Shire (SHPG) 19 according to iVolatility.
July 22, 2014
10:48 EDTSHPGOptions with decreasing implied volatility
Options with decreasing implied volatility: IGT YHOO LYK ATHN CMG SWKS NFLX SHPG SNDK MTG
05:59 EDTSHPGStocks with implied volatility below IV index mean; INTC SHPG
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July 21, 2014
10:27 EDTSHPGUBS pharma and federal affairs analysts hold an analyst/industry conference call
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10:02 EDTSHPGOn The Fly: Analyst Downgrade Summary
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08:50 EDTSHPGShire downgraded to Neutral from Buy at Buckingham
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08:01 EDTSHPGAbbVie acquisition positive, says Argus
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07:59 EDTSHPGShire downgraded to Market Perform from Outperform at Leerink
Leerink downgraded Shire (SHPG) on Friday to Market Perform citing the takeover by AbbVie (ABBV) as it does not expect competitive bids to emerge.
06:14 EDTSHPGStocks with implied volatility below IV index mean; INTC SHPG
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July 18, 2014
18:04 EDTSHPGAbbVie purchase of Shire worth the premium, Barron's reports
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16:47 EDTSHPGMarket ends week higher as earnings, M&A offset geopolitical tensions
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11:25 EDTSHPGOptions with decreasing implied volatility
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10:38 EDTSHPGShire downgraded to Fair Value from Buy at CRT Capital
Shire (SHPG) is being acquired by AbbVie (ABBV).
10:34 EDTSHPGShire downgraded to Neutral from Overweight at Piper Jaffray
Shire (SHPG) is being acquired by AbbVie (ABBV).
10:30 EDTSHPGAbbVie says can't back out of Shire deal based on tax law change, Bloomberg says
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09:29 EDTSHPGAbbVie, Shire says merger should help in enhanced buyback and dividend programs
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06:23 EDTSHPGShire raises FY14 EPS to low-to-mid 30% growth from mid-to-high teens
Raises FY14 product sales guidance to growth in high teens from mid-to-high teens. Shire continues to expect royalties and other revenues to be 10%-15% lower than 2013.
06:19 EDTSHPGShire reports Q2 EPS $2.67, consensus $2.45
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05:17 EDTSHPGAbbVie, Shire agree on merger worth GBP32B pounds
The boards of AbbVie (ABBV) and Shire (SHPG) announced that they have reached agreement on the terms of a recommended combination of Shire with AbbVie. Under the terms of the Merger, Shire shareholders will be entitled to receive per share GBP 24.44 in cash and 0.8960 new AbbVie shares. Immediately following the transaction, Shire shareholders are expected to hold new AbbVie Shares representing approximately 25% of the issued share capital of new AbbVie. AbbVie expects the transaction to be accretive to adjusted earnings per share in the first year following completion, growing to above $1.00 per share by 2020, with "material ongoing financial and operating benefits." The AbbVie board also expects the transaction to reduce New AbbVie's effective tax rate to approximately 13% by 2016. The Shire board said it "considers the terms of the Transaction to be fair and reasonable." In order to undertake the transaction, AbbVie has formed a new company, New AbbVie, which is incorporated in Jersey, Shire's current place of incorporation. Following completion of the Transaction, New AbbVie will become the holding company of the Shire Group and the AbbVie Group. It is intended that the New AbbVie Shares will be listed on the New York Stock Exchange.
05:12 EDTSHPGAbbVie to acquire Shire for 52.48 pounds per share in cash, stock
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