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Stock Market & Financial Investment News

News Breaks
May 13, 2014
09:07 EDTRGLSRegulus Therapeutics initiated with an Outperform at Brinson Patrick
Target $16.
News For RGLS From The Last 14 Days
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April 9, 2015
08:10 EDTRGLSRegulus to present positive results for HCV candidate RG-101
Regulus announced multiple presentations related to RG-101, a GalNAc-conjugated anti-miR targeting microRNA-122 for the treatment of chronic Hepatitis C Virus infection scheduled for presentation at The International Liver Congress.The new clinical data demonstrates that RG-101 shows dose responsive pharmacodynamics with maximal changes at 2 mg/kg in healthy volunteers and no drug-drug interactions observed when administered in combination with the direct acting anti-viral drug simeprevir. Additional data supports the evaluation of RG-101 in human clinical trials. Following subcutaneous administration, rapid absorption and clearance of RG-101 was observed in plasma with rapid uptake and efficient conversion to unconjugated oligonucleotide in the liver and reduced concentrations in kidney.
April 8, 2015
19:46 EDTRGLSOn The Fly: After Hours Movers
UP AFTER EARNINGS: Apogee (APOG), up 6.4%... Pier 1 Imports (PIR), up 4.4%. ALSO HIGHER: Inovio Pharmaceuticals (INO), up 5.6% after being selected by DARPA to lead $45M Ebola prevention program. DOWN AFTER EARNINGS: Alcoa (AA), down 3.5%... Bed Bath & Beyond (BBBY), down 3.5%. ALSO LOWER: Zynga (ZNGA), down 10.3% after announcing CEO transition... Memorial Production (MEMP), down 2.9% after filing to sell 4.6M common units owned by MRD Holdco... Regulus (RGLS), down 2.2% after filing to sell 3.3M shares for Isis Pharmaceuticals.
16:11 EDTRGLSRegulus files to sell 3.3M shares for Isis Pharmaceuticals
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09:20 EDTRGLSOn The Fly: Pre-market Movers
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April 7, 2015
19:10 EDTRGLSOn The Fly: After Hours Movers
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16:12 EDTRGLSRegulus up 5% after RG-125 selected as clinical candidate by AstraZeneca
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16:12 EDTRGLSRegulus RG-125 selected as clinical candidate by AstraZeneca
Regulus Therapeutics (RGLS) announced the selection of RG-12, a GalNAc-conjugated anti-miR targeting microRNA-103/107, or miR-103/107, for the treatment of Non Alcoholic Steatohepatitis, or NASH, in patients with type 2 diabetes/pre-diabetes, as a clinical candidate by AstraZeneca (AZN) under the companies' strategic alliance to discover, develop and commercialize microRNA therapeutics. RG-125 is the first compound from the alliance to be selected for clinical development by AstraZeneca. In connection with the candidate selection, AstraZeneca will pay Regulus $2.5M and will assume development of the program following acceptance of an Investigational New Drug application. In the near term, Regulus and AstraZeneca plan to submit key preclinical data on the RG-125 program to be presented at a scientific meeting later this year and expect to initiate a Phase I study of RG-125 in humans by the end of 2015.
April 6, 2015
07:56 EDTRGLSAchillion price target lowered to $20 from $25 at Deutsche Bank
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