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February 10, 2014
07:32 EDTREGNRegeneron, Bayer announce positive Phase 3 Eylea trial results
Regeneron and Bayer HealthCare announced that in the Phase 3 VISTA-DME trial of EYLEA Injection for the treatment of diabetic macular edema, EYLEA 2 milligrams dosed monthly and EYLEA 2 mg dosed every two months showed a sustained improvement from baseline in best corrected visual acuity at week 100, compared to laser photocoagulation. After two years, patients receiving EYLEA 2Q4 had a mean change from baseline in BCVA of 11.5 letters. Patients receiving EYLEA 2Q8 had a mean change from baseline in BCVA of 11.1 letters. Patients in the laser photocoagulation treatment group had a mean change from baseline in BCVA of 0.9 letters. In this trial, EYLEA was generally well tolerated with a similar overall incidence of adverse events, ocular serious AEs, and non-ocular serious AEs across the EYLEA treatment groups and the laser control group. Bayer HealthCare and Regeneron are collaborating on the global development of EYLEA.
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December 12, 2014
08:01 EDTREGNPiper predicts two large-cap biotechs could be acquired in 2015
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