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November 15, 2012
18:04 EDTRDUSRadius Health withdraws registration statement on form S-1
In a regulatory filing Radius said: Radius Healtth hereby applies for withdrawal of the company’s registration statement on Form S-1 filed with the Securities and Exchange Commission on February 6, 2012 and amended on September 28, October 19 and November 7. Pursuant to Rule 477 under the Securities Act of 1933, as amended the company is withdrawing the Registration Statement, which has not been declared effective, because the proposed public offering under the Registration Statement was abandoned due to general market conditions. Since the Registration Statement was not declared effective by the Commission, no shares of common stock as described in the Registration Statement were sold. In addition, the Company hereby applies for withdrawal of the Company’s Registration Statement on Form 8-A, filed with the Commission on November 5.
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December 22, 2014
16:09 EDTRDUSRadius Health price target raised to $52 from $26 at Cantor
Cantor doubled its price target on Radius Health to $52 from $26 after the company reported Phase III trial data the firm views as having significantly de-risked its development of abaloparatide-SC for the treatment of severe post-menopausal osteoporosis. Cantor maintains its Buy rating on Radius shares.
06:20 EDTRDUSRadius Health to host conference call
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05:27 EDTRDUSRadius Health reports 'significant' progress towards abaloparatide development
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05:23 EDTRDUSRadius Health ACTIVE Phase 3 clinical trial meets primary endpoint
Radius Health announced positive top-line 18-month fracture results from the company's Phase 3 clinical trial, known as ACTIVE, evaluating the investigational drug abaloparatide-SC for potential use in the reduction of fractures in postmenopausal osteoporosis. On the primary endpoint, the investigational drug abaloparatide-SC achieved a statistically significant 83% reduction of incident vertebral fractures as compared to the placebo-treated group. The ACTIVE trial included an open-label teriparatide injection treatment group that showed a statistically significant 78% reduction of incident vertebral fractures as compared to the placebo-treated group. On the secondary endpoints as compared to placebo, abaloparatide-SC achieved a statistically significant fracture-rate reduction of 43% in the adjudicated non-vertebral fracture subset of patients; a statistically significant reduction of 41% in the adjudicated clinical fracture group, which includes both vertebral and non-vertebral fractures; and a statistically significant difference in the time to first incident non-vertebral fracture in both the adjudicated non-vertebral fracture and the clinical fracture subset of patients.

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