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November 8, 2012
11:52 EDTPSTIPluristem lack of disclosure on patient death in legal gray area, Bloomberg says
Pluristem Therapeutics' (PSTI) stock soared and at least two top executives profited in spite of the fact that a patient reportedly died months after using its experimental stem cell treatment, according to Bloomberg. The company has yet to make an announcement of the girl’s death, which may put it in a legal gray area in regards to U.S. securities laws, the report noted. Reference Link
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October 27, 2014
05:26 EDTPSTIPluristem PLX-RAD cells to be studied at Case Western Reserve University
Pluristem Therapeutics announced that researchers at Case Western Reserve University will conduct a preclinical study of the Company's PLacental expanded-RAD, or PLX-RAD, cells. The study will evaluate whether PLX-RAD cells increase the success rate of human umbilical cord blood transplantation. Umbilical cord blood cells are transplanted to replace a patient's unhealthy bone marrow cells. When successful, a transplant can treat bone marrow failure, which can result from immune system disorders, genetic diseases, and leukemia treatment. When cord blood cells are administered to a patient, they travel to the bone marrow and produce healthy white and red blood cells and platelets after the patient's own abnormal cells have been eliminated. Sometimes, however, the cord blood cells fail to take hold and the transplant fails. The study at Case Western Reserve will research the feasibility of using PLX-RAD cells to help the cord blood to engraft more effectively, resulting in higher rates of successful transplantation and treatment. PLX-RAD cells are also being studied by the U.S. National Institutes of Health, NIH, for the treatment of acute radiation syndrome, or ARS, which involves bone marrow failure after exposure to high levels of radiation, as can happen after a nuclear catastrophe.
October 21, 2014
05:09 EDTPSTIPluristem moves to large-scale manufacturing after second product line completed
Pluristem Therapeutics announced that it has completed development of its second major product line, and can now begin manufacturing the cells on a large-scale at its state-of-the art facility in order to meet demand for anticipated studies in a range of hematologic conditions. This second cell product candidate, called PLX-RAD, was created using Pluristem's proprietary three dimensional cell expansion technology platform. The company's first product, PLX-PAD, is already in clinical trials for the treatment of peripheral artery disease, muscle injury and pulmonary arterial hypertension. Pluristem's development plan for the PLX-RAD cells considers numerous potential clinical indications such as: enhancement of engraftment of transplanted hematopoietic stem cells for the treatment of bone marrow deficiency, which can result from immune system disorders, genetic diseases, and treatment of leukemia and other blood cancers; treatment of bone marrow deficiency in patients who have undergone chemotherapy; treatment of acute radiation syndrome, or ARS in conjunction with the U.S. National Institutes of Health's National Institute of Allergy and Infectious Diseases.
October 20, 2014
07:19 EDTPSTIIBC Life Sciences to hold a conference
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