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January 8, 2014
08:58 EDTPPHM, PNT, SNTAThree pharma companies have good partnering prospects, says Roth Capital
Roth Capital believes that Peregrine (PPHM), Palatin (PTN), and Synta (SNTA) have good odds of signing partnership deals in the "relative near term." The firm keeps Buy ratings on all three stocks.
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April 23, 2014
07:37 EDTPPHMPeregrine announces investigator-sponsored combination trial with Bristol-Myers
Peregrine Pharmaceuticals (PPHM) announced the opening of an investigator-sponsored trial, or IST, of its investigational immunotherapy bavituximab in combination with Bristol-Myers Squibb's (BMY) ipilimumab, for the treatment of advanced melanoma. Bavituximab is an upstream immune checkpoint inhibitor that targets phosphatidylserine, or PS, a highly immunosuppressive molecule exposed on cells that line tumor blood vessels and tumor cells. Preclinical data in a model of melanoma demonstrate that the combination of a bavituximab equivalent and ipilimumab yield enhanced anti-tumor activity compared to ipilimumab alone. The trial is being conducted at the University of Texas Southwestern Medical Center, Dallas, and led by Arthur E. Frankel, M.D., Associate Professor of Internal Medicine at the Simmons Comprehensive Cancer Center. Bavituximab, Peregrine's lead immuno-oncology candidate, is being evaluated in second-line non-small cell lung cancer, as part of the SUNRISE pivotal Phase III clinical trial.
April 14, 2014
08:02 EDTSNTASynta sells $5M in common stock directly to affiliate of board member
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