Opexa Therapeutics held a conference call Conference call to discuss the option and license agreement with Merck Serono for development of Tcelna for treatment of Multiple Sclerosis was held on February 5 at 8:30 am and has a webcasted replay available. Webcast Link
Opexa granted new T-cell patents covering Tcelna Opexa announced the issuance of four additional key patents covering its broad T-cell immunotherapy platform. The recent allowances bring the number of granted U.S. and international patents in Opexa's patent portfolio to 160, including in-licensed patents. The expansion of Opexa's intellectual property portfolio further strengthens the patent estate surrounding Tcelna, Opexa's personalized T-cell immunotherapy in development for the treatment of secondary progressive multiple sclerosis. Recently-granted European Patent Nos. 1546719, 2016414 and 2420833 are directed to Opexa's proprietary methods for preparing individualized T-cell vaccines, while European Patent No. 2363710 is directed to the autologous T-cell vaccine compositions themselves. The claims cover the use of particular immunodominant epitopes found in myelin basic protein, proteolipid protein and myelin oligodendrocyte protein in the preparation of such T-cell vaccines, as well as the identification and use of specific antigenic epitopes that are disease-relevant for individual patients from these and other polypeptide antigens.