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January 16, 2014
04:55 EDTOMED, OMED, OMED, MACK, MACK, MACK, KPTI, KPTI, KPTIAmerican Gastroenterological Association to hold a symposium
2014 Gastrointestinal Cancers Symposium is being held in San Francisco on January 16-18.
News For OMED;MACK;KPTI From The Last 14 Days
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April 24, 2014
07:45 EDTKPTIKaryopharm initiates Phase 2 study of Selinexor
Karyopharm Therapeutics announced the initiation of a Phase 2 trial of its novel, oral Selective Inhibitor of Nuclear Export, or SINE, compound Selinexor in patients with advanced gynecologic malignancies including cervical, ovarian and uterine carcinomas. In this Phase 2 study, patients will receive Selinexor at a dose of 50mg/m2, twice a week. The primary goal of the study is to determine the disease control rate assessed according to RECIST criteria. The secondary goal of the study is to evaluate safety and tolerability. Quality of life will also be evaluated.
April 21, 2014
07:06 EDTKPTIKaryopharm announces Phase 1 trial of Selinexor
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April 15, 2014
16:08 EDTKPTIKaryopharm announces initiation of Phase 1 study of Selinexor-decitabine combo
Karyopharm Therapeutics announced the initiation of a Phase 1 combination trial of its novel, oral Selective Inhibitor of Nuclear Export compound Selinexor in combination with the DNA methylation inhibitor decitabine in patients with relapsed or refractory acute myeloid leukemia, or AML, and in patients age 60 years with newly diagnosed AML. Sharon Shacham, Karyopharm's founder, President and Chief Scientific Officer, commented, "This first combination study of Selinexor represents a significant milestone for the company as we look to broaden the scope of SINE compounds in the treatment of cancers."

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