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February 20, 2014
08:57 EDTOMED, BAYRYOncoMed commences third Phase 1b clinical trial for OMP-54F28
OncoMed Pharmaceuticals (OMED) announced the initiation of patient treatment for its third multi-center Phase 1b clinical trial of OMP-54F28 with carboplatin and paclitaxel in patients with platinum-sensitive ovarian cancer. OMP-54F28 is a first-in-class decoy receptor targeting the Wnt pathway and is part of OncoMed's collaboration with Bayer Pharma AG (BAYRY). The Phase 1b clinical trial of OMP-54F28 in combination with carboplatin and paclitaxel is a dose-escalation study in patients with recurrent platinum-sensitive ovarian cancer. Primary objectives of the trial are to evaluate safety of this combination regimen and determine a recommended Phase 2 dose for OMP-54F28 in combination with carboplatin and paclitaxel. Key secondary and exploratory objectives include evaluation of the pharmacokinetics and pharmacodynamics of OMP-54F28, as well as the efficacy of this combination. Tumor tissue from patients will be used to explore predictive biomarker hypotheses related to the efficacy of OMP-54F28.
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March 26, 2015
11:13 EDTBAYRYBofA/Merrill European pharma analyst holds an analyst/industry conference call
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10:04 EDTBAYRYOn The Fly: Analyst Downgrade Summary
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05:31 EDTBAYRYBayer downgraded to Neutral from Buy at UBS
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March 25, 2015
07:17 EDTBAYRYSociety for Reproductive Investigation to hold scientific meeting
62nd Annual Scientific Meeting: SRI 2015 is being held in San Francisco on March 25-28.
March 20, 2015
07:41 EDTBAYRYAmerican Academy of Dermatology to hold annual meeting
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