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News Breaks
March 3, 2014
05:50 EDTOHRPOhr Pharmaceutical, CSHL announce trodusquemine JV
Ohr Pharmaceutical and global cancer research center Cold Spring Harbor Laboratory, or CSHL, announced the establishment of DepYmed Inc., a new joint venture to develop trodusquemine and related analogs. The new joint venture will be a private entity, initially with equal ownership by Ohr and Cold Spring Harbor Laboratory. The two partners will seek funding and contribute to the research and development of trodusquemine and also newly patented analogs. The goal is to take the program into the clinic and to demonstrate proof of concept. Various options to fund later stage clinical trials will be explored.
News For OHRP From The Last 14 Days
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March 27, 2015
10:20 EDTOHRPOhr Pharmaceutical price target lowered to $15 from $25 at Cowen
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10:01 EDTOHRPHigh option volume stocks
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09:30 EDTOHRPOhr Pharmaceutical downgraded to Neutral from Buy at Chardan
Price target $8.
09:26 EDTOHRPOn The Fly: Pre-market Movers
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07:53 EDTOHRPOhr Pharmaceutical data better than may seem, says Brean Capital
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07:49 EDTOHRPOhr Pharmaceutical to host conference call
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07:14 EDTOHRPOhr Pharmaceutical announces final topline data from OHR-102 Phase II study
Ohr Pharmaceutical announced the topline results from the exploratory Phase II IMPACT study evaluating OHR-102 combination therapy for the treatment of the wet form of age-related macular degeneration, or wet-AMD. In the intent-to-treat, or ITT-LOCF population with classic containing choroidal neovascularization, or CNV, 42% of the patients receiving OHR-102 achieved a 3 line gain at nine months, as compared to 28% in the Lucentis monotherapy group. Less of a benefit was seen in the overall population. The classic containing CNV population represents approximately two thirds of the total wet-AMD population. The positive effect on visual acuity in classic CNV was seen early in the course of treatment and continued to increase through the end of the study, supporting the planned Phase III development program. In patients with classic CNV, mean gains in visual acuity were +10.5 letters for the OHR-102 combination arm and +5.4 letters with Lucentis monotherapy, a clinically meaningful benefit of +5.1 letters. The mean number of injections between the treatment arms, the primary endpoint of the study, was not meaningfully different.

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