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News Breaks
February 20, 2014
09:00 EDTOHRPOhr Pharmaceutical announces positive case report on Squalamine
Ohr Pharmaceutical announced that a case report on the first patient treated in an ongoing investigator sponsored trial with Squalamine eye drops in proliferative diabetic retinopathy was presented at the 37th Annual Macula Society Meeting, in Key Largo, Florida. Diabetic retinopathy is the second most common cause of vision loss. In PDR, abnormal blood vessels grow from the retina into the vitreous cavity of the eye, resulting in blindness if untreated. This ongoing 5 patient OHR-003 trial is designed to determine the efficacy of topical Squalamine Lactate Ophthalmic Solution, 0.2%, in the treatment of retinal neovascularization resulting from proliferative diabetic retinopathy. The endpoints include regression of neovascularization, anatomical measurements, visual acuity, and safety parameters.
News For OHRP From The Last 14 Days
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March 27, 2015
10:20 EDTOHRPOhr Pharmaceutical price target lowered to $15 from $25 at Cowen
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10:01 EDTOHRPHigh option volume stocks
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09:30 EDTOHRPOhr Pharmaceutical downgraded to Neutral from Buy at Chardan
Price target $8.
09:26 EDTOHRPOn The Fly: Pre-market Movers
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07:53 EDTOHRPOhr Pharmaceutical data better than may seem, says Brean Capital
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07:49 EDTOHRPOhr Pharmaceutical to host conference call
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07:14 EDTOHRPOhr Pharmaceutical announces final topline data from OHR-102 Phase II study
Ohr Pharmaceutical announced the topline results from the exploratory Phase II IMPACT study evaluating OHR-102 combination therapy for the treatment of the wet form of age-related macular degeneration, or wet-AMD. In the intent-to-treat, or ITT-LOCF population with classic containing choroidal neovascularization, or CNV, 42% of the patients receiving OHR-102 achieved a 3 line gain at nine months, as compared to 28% in the Lucentis monotherapy group. Less of a benefit was seen in the overall population. The classic containing CNV population represents approximately two thirds of the total wet-AMD population. The positive effect on visual acuity in classic CNV was seen early in the course of treatment and continued to increase through the end of the study, supporting the planned Phase III development program. In patients with classic CNV, mean gains in visual acuity were +10.5 letters for the OHR-102 combination arm and +5.4 letters with Lucentis monotherapy, a clinically meaningful benefit of +5.1 letters. The mean number of injections between the treatment arms, the primary endpoint of the study, was not meaningfully different.

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