NxStage Medical receives FDA clearance for home nocturnal hemodialysis NxStage Medical announced that the FDA has cleared its System One to perform hemodialysis overnight while the patient is at home sleeping, known as home nocturnal hemodialysis. NxStage's System One is the first and only hemodialysis machine cleared by the FDA for this indication. Home nocturnal hemodialysis is an important patient option associated with a number of lifestyle and clinical advantages. By doing therapy while sleeping, the patient frees up their day to pursue other activities therefore reducing the overall burden of therapy. A longer, overnight therapy also allows greatly expanded flexibility in dialysis dose and schedule, better enabling physicians to match the dialysis prescription to individual patient needs.