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December 6, 2012
16:09 EDTNVAXNovavax' Phase I RSV vaccine data published in Vaccine
Novavax today announced that the journal Vaccine has published the company's data from its 2011 Phase I clinical trial of its respiratory syncytial virus, RSV, fusion, F,recombinant nanoparticle vaccine candidate. The paper was authored by a team of researchers and clinicians at Novavax and Dr. Pedro Piedra of Baylor College of Medicine. Findings from the trial were announced in October 2011 and presented in September by Novavax at the Respiratory Virus Symposium,RSV 2012, meeting in Santa Fe, New Mexico.
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July 30, 2015
08:39 EDTNVAXNovavax reports positive data from Phase 2 trial of Quadrivalent
Novavax announced positive top-line data from a Phase 2 clinical trial of its recombinant quadrivalent seasonal influenza virus-like particle, or VLP, vaccine candidate. This project has been funded in whole or in part with Federal funds from the Office of the Assistant Secretary for Preparedness and Response, Biomedical Advanced Research and Development Authority, Department of Health and Human Services under the Company’s contract with HHS-BARDA. The trial demonstrated that the Seasonal Influenza VLP vaccine candidate was well-tolerated with no vaccine-related serious adverse events. The trial met its immunogenicity targets and demonstrated potential to meet the Center for Biological Evaluation and Research criteria for accelerated approval. Novavax’ technology platform enables the creation of recombinant, strain-specific VLPs. Novavax’ Seasonal Influenza VLP consists of VLPs representing four different strains of influenza virus, each expressing strain-specific hemagglutinin and neuraminidase antigens. This dose-ranging clinical trial was designed to evaluate the safety and immunogenicity of the Seasonal Influenza VLP in 400 healthy adults. The primary outcomes of the trial assessed safety and tolerability of the Seasonal Influenza VLP and quantified immune responses to each of the four influenza strains based on hemagglutination-inhibiting antibody titers. The secondary outcomes evaluated neuraminidase-inhibiting antibody titers for all four influenza strains.
July 21, 2015
11:00 EDTNVAXNovavax price target raised to $15 from $10.50 at Piper Jaffray
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09:21 EDTNVAXOn The Fly: Pre-market Movers
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08:34 EDTNVAXNovavax announces positive top-line data from Phase 1 ebola vaccine trial
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