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March 24, 2014
12:07 EDTISIS, P, UPS, ARWR, HLF, GILD, AAPL, NUSOn The Fly: Midday Wrap
Stocks on Wall Street were lower at midday following reports on the state of manufacturing in the U.S., China and the European Union. The Purchasing Managers' Indexes, or PMIs, showed that manufacturing activity contracted last month in China but that it had expanded again in the U.S. and the EU. ECONOMIC EVENTS: In the U.S., Markit's manufacturing PMI for March fell to 55.5 from February's 57.1 reading. The reading was 1 point below the consensus forecast, but was still strongly in expansionary territory, as 50 is the dividing line between expansion and contraction. In China, Markit's flash PMI came in at 48.1, falling short of expectations for a 48.7 reading. In Europe, the PMI for the euro area as a whole came in at 53.2, which was just below last month's 32-month high reading of 53.3. COMPANY NEWS: Shares of Nu Skin Enterprises (NUS) surged nearly 19% near midday after the company's China business was penalized only $540,000 for direct sales of certain products. Nu Skin said it is already taking steps to correct the issues raised in the AIC reviews and that it is not aware of any other material enforcement investigations currently pending in China. Research firm Deutsche Bank said it expects Nu Skin to announce a "significant" share repurchase program over the next several quarters after the China investigation was resolved with "modest" fines. Deutsche thinks today's news lifts an overhang on Nu Skin and keeps a Buy rating on the stock with a $110 price target. Meanwhile shares of Nu Skin's multi-level marketing peer Herbalife (HLF), which has also been accused of impropriety in China, are up about 8%. Herbalife had its own news this morning as well, as it announced that it has amended and restated its agreement with Carl Icahn and will nominate three new Icahn designees for election to the company’s board. MAJOR MOVERS: Among the notable gainers was MicroVision (MVIS), which jumped 20% after announcing that it has agreed to supply customized PicoP display modules to shipping giant UPS (UPS). Also higher was Symantec (SYMC), which rose 2% after research firm BMO Capital upgraded the stock and said it believes all strategic options, including a sale or divestiture of underperforming assets, will be considered following the company's recent termination of its CEO. Among the noteworthy losers was Arrowhead Research (ARWR), which dropped more than 15%. Research firm Piper Jaffray attributed the move lower to competitor ISIS Pharmaceuticals (ISIS) having announced preclinical data on its own antisense compound targeting hepatitis B virus, which is a clinical area that Arrowhead is also exploring. A number of other biotechnology companies' shares were also lower, with Oppenheimer attributing the continued weakness in the sector to investor concerns that were sparked by a letter sent Friday by several members of Congress to Gilead (GILD) regarding the price of its Hepatits C drug, Sovaldi. Also lower were shares of Internet radio company Pandora (P), which slid almost 9% after Billboard reported on Friday that Apple (AAPL) is considering launching a new music service and is also weighing a new iTunes app for Android smartphones. INDEXES: Near midday, the Dow was down 52.55, or 0.32%, to 16,250.22, the Nasdaq was down 66.01, or 1.54%, to 4,210.78, and the S&P 500 was down 12.25, or 0.66%, to 1,854.27.
News For NUS;HLF;P;AAPL;ARWR;ISIS;GILD;UPS From The Last 14 Days
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November 16, 2015
08:27 EDTARWRArrowhead to hold an analyst and investor reception
Management hosts an Analyst and Investor Reception to discuss ARC-520 and key data presented at the 66th Annual Meeting of AASLD in San Francisco on November 16 at 9:30 pm. Webcast Link
07:50 EDTPUBS to hold a conference
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06:37 EDTAAPLApple's Cook: No plans to make 'converged' MacBook and iPad, Independent reports
Apple has no plans to build a "converged" MacBook and iPad, the Independent reports, citing CEO Tim Cook. "We feel strongly that customers are not really looking for a converged Mac and iPad," Cook said. "Because what that would wind up doing, or what we're worried would happen, is that neither experience would be as good as the customer wants. So we want to make the best tablet in the world and the best Mac in the world. And putting those two together would not achieve either. You'd begin to compromise in different ways." Reference Link
06:19 EDTAAPLApple News fails to impress publishers, Digiday reports
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06:05 EDTAAPLApple price target lowered to $140 from $150 at UBS
UBS analyst Steven Milunovich lowered his price target for Apple to $140 from $150 saying the stock's multiple is likely to be pressured until supply chain concerns are resolved. UBS analyst Arthur Hsieh indicates Hon Hai's Q4 iPhone assembly order forecast has been cut and should be down 10% year-over-year, Milunovich tells investors in a research note. The analyst is unclear what the order pullback means for iPhone shipments, but notes "it is not encouraging." Milunovich maintains his above-consensus December estimates for Apple, but trimmed his estimates for the March quarter. He keeps a Buy rating on Apple.
November 15, 2015
20:17 EDTGILDGilead presents results from four Phase 3 studies of sofosbuvir/velpatasvir
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19:49 EDTAAPLApple CEO Cook expects 'huge' Watch sales this year, IE says
In an interview with Irish Independent published Sunday, Apple CEO Tim Cook said he expects "huge" Apple Watch sales this year. Cook added that he sees iPad sales rebounding, and said the company does not plan a combined iPad-Mac device. Reference Link
18:28 EDTARWRArrowhead reports data on anti-hepatitis B effects of ARC-520 in chimpanzees
Arrowhead announced the presentation of data demonstrating that ARC-520, its drug candidate against chronic hepatitis B infection, leads to "robust, sustained anti-viral effects in chimpanzees with chronic HBV," according to the company. Arrowhead also reported a new discovery that HBV DNA integrated into the host genome is "likely an important source of HBV surface antigen production, particularly in chimps that are negative for hepatitis B e-antigen." ARC-520 led to a drop in circulating HBsAg, with the degree of HBsAg reduction correlating with HBeAg status. HBeAg-positive and negative chimps demonstrated HBsAg reductions of 96.8%-99.8% and 68.4%-87.4%, respectively, with an intermediate response in a chimp transitioning from HBeAg positive to negative. In addition, one chimp seroconverted for HBeAg during ARC-520 therapy and had a sustained virologic response with respect to HBeAg, HBV DNA, and HBsAg. This persisted off therapy and through at least 32 weeks after ARC-520 and NUC therapy was removed. A second chimp demonstrated effects consistent with immunologic reactivation. Arrowhead also found that the predominant form of liver HBV DNA differed in HBeAg-negative versus HBeAg-positive chimps. Most HBV DNA in HBeAg-positive chimps was cccDNA, while less than 5% of HBV DNA in HBeAg-negative chimps was cccDNA. In addition, HBV RNA profiles in HBeAg-negative chimps were consistent with transcripts arising from integrated DNA. "These data and others, strongly suggest that integrated DNA is likely an important source of HBsAg production in HBeAg-negative chimps," claimed the company. "Direct confirmatory data" was obtained by treating HBeAg negative chimps with a siRNA designed to target transcripts originating from integrated HBV DNA. Up to an additional 99% of HBsAg knockdown was achieved, resulting in overall relative knockdown levels similar to those observed using ARC-520 in HBeAg-positive chimps. Arrowhead said it has incorporated one of these RNAi triggers and one targeting predominantly cccDNA derived transcripts into a new complementary drug candidate, ARC-521, that is planned to be in clinical trials in 2016. The company noted it plans to present additional data at the Hep Dart conference in December demonstrating that two of four HBeAg-positive chimps exhibited signs of immune reactivation, "which is believed to be a necessary step toward achieving a functional cure of HBV."
15:47 EDTGILDGilead reports data from multiple studies of Viread, TAF, others
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November 13, 2015
16:40 EDTAAPLAppaloosa gives quarterly update on stakes
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16:26 EDTAAPLStocks end week lower as retail gets routed
Stocks ended the week sharply lower after weak retail earnings reports, highlighted by Macy's (M), were followed by a worse than expected government report on retail sales performance in October. MACRO NEWS: In the U.S., retail sales rose 0.1% in the month of October, versus expectations for an increase of 0.3%. When autos and gas are removed, the core reading was up 0.3%, versus expectations for a rise of 0.4%. Producer prices fell 0.4%, versus expectations for them to be up 0.2%. When food and energy are removed, the core reading was down 0.3%, versus expectations for it to be up 0.1%. Business inventories grew 0.3% in September while sales were flat compared to August. Consumer sentiment, as measured by the preliminary print from the University of Michigan survey, improved 3.1 points to 93.1 in November, which was better than the 91.5 reading that was expected. In Europe, data showed that eurozone's economy grew by just 0.3% in the third quarter, which was a slowdown from the 0.4% GDP growth recorded three months earlier and weaker than the 0.4% consensus growth forecast. In China, exports declined for a fourth straight month in October, sliding 3.6%, while imports fell for a 12th straight month, declining 16% in yuan terms. China's foreign-exchange reserves rose in October for the first time in six months, increasing to $3.53T from $3.51T at the end of September, the People's Bank of China reported. Industrial output in China rose 5.6% in October, matching March's reading as the weakest since 2008. Retail sales climbed 11% last month, beating expectations. COMPANY NEWS: Shares of retailers broadly declined following disappointing earnings reports and commentary from a number of department store operators, including Macy's, Nordstrom (JWN) and J.C. Penney (JCP). Weather was cited by a number of them, and analysts also pointed to the continued rise in competition felt by brick-and-mortar retailers from e-commerce players, mainly (AMZN)... Among earnings reporters outside of the retail sector, Viacom (VIAB) and Rackspace (RAX) rose immediately following their reports, while Cisco (CSCO), Priceline (PCLN), Hertz (HTZ), and Advance Auto Parts (AAP) fell right after their own... During the company's investor meeting, McDonald's (MCD) raised its global refranchising target to 4,000 restaurants through 2018 with a new long-term goal to become 95% franchised, announced plans to increase its dividend by 5% and said that after "robust" debate it had decided to not pursue a REIT spin-off transaction for its real estate holdings... Anheuser-Busch InBev (BUD) and SABMiller (SBMRY) came to terms on a deal to combine the companies in a transaction worth $107B. In relation to their deal, Molson Coors (TAP) agreed to purchase SABMiller's 58% stake in MillerCoors, the joint venture formed in the United States in 2008, in a deal valued at $12B. Molson Coors was the biggest winner in terms of percentage stock gains immediately following the announcements, rising over 4% on Wednesday... Mylan (MYL) jumped after the company's offer to acquire Perrigo (PRGO) failed, ending a seven-month fight between the two drugmakers. Perrigo Chief Executive Officer Joseph Papa said he was "delighted" that his company's shareholders rejected the offer and the company added that it will immediately commence its previously announced $2B share buyback program, but its shares slid in the wake of the shareholder vote... PayPal (PYPL) shares saw three straight days of losses after the Wall Street Journal reported that Apple (AAPL) is working on a mobile payments service that could compete with the firm's Venmo platform... Angie's List (ANGI) advanced after IAC/InterActiveCorp (IACI), the parent company of HomeAdvisor, made public a $8.75 per share cash buyout offer. Yelp (YELP), which also connects people with local businesses via its web-based and mobile services, also rose following the revelation of the takeout bid for Angie's List... Alibaba Group (BABA) reported blockbuster sales for the 11.11 shopping festival, better known as "Singles' Day." By the end of Wednesday in China, gross merchandise volume on Alibaba's platforms hit $14.3B, far exceeding last year's 24-hour total of $9.3B and topping the company's $11B forecast. INDEXES: The Dow lost about 3.7% to close at 17,245.24, the S&P 500 fell about 4.25% to close at 2,023.04, and the Nasdaq declined about 3.6% to close at 4,927.88.
16:00 EDTAAPLOptions Update; November 13, 2015
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15:04 EDTAAPLLeerink digital health analyst holds analyst/industry conference call
Digital Health Analyst Wardell discusses Fitbit and how many units will it sell in Q4, the Apple Watch and whether it is in a different product category than Fitbit on an Analyst/Industry conference call to be held on November 17 at 12:30 pm.
11:57 EDTAAPLGoogle rolls out Chrome beta for iOS, 9to5Mac reports
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10:15 EDTAAPLApple breaks below support at $115, levels to watch
The shares are down over 1.5% to $113.95. At that price next support is at $111.73. Resistance is at $115.
10:09 EDTAAPLApple could launch second-generation Apple Watch by June 2016, AI reports
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09:35 EDTAAPLActive equity options trading on open
Active equity options trading on open: AAPL CSCO FB BAC BABA MSFT NFLX INTC JCP AMZN C
08:28 EDTARWRAmerican Association for Study of Liver Diseases to hold annual meeting
The Liver Meeting 2015 is being held in San Francisco on November 13-17.
06:17 EDTAAPLApple Music coming to Sonos 'soon'
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06:15 EDTAAPLApple's Beats Music ending on November 30
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