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February 18, 2014
08:07 EDTMSTXMast Therapeutics reports positive data from MST-188 study
Mast Therapeutics announced new data from its randomized, placebo-controlled, nonclinical study of MST-188 in a model of chronic heart failure. MST-188 resulted in statistically significant and progressive reductions in troponin-I, at both 1 week and 2 weeks after MST-188 administration. Specifically, at 2 weeks post-administration, compared to baseline values, mean reduction troponin was 46.7% for low-dose MST-188 and 48.8% for high-dose MST-188. In contrast, troponin increased 7.7% in the control group.
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