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November 12, 2012
18:05 EDTMNOVMedicNova announces publication of positive phase 2 clinical results
MediciNova announced the publication of positive Phase 2 clinical results in two asthma studies in the Journal of Asthma. The publication reports on two Phase 2a clinical trials conducted by MediciNova, MN-221-CL-004 and MN-221-CL-005, which assessed the safety, tolerability, and FEV1 improvements in mild-moderate and moderate-to-severe asthmatics, respectively. MN-221 is designed to treat acute exacerbations via intravenous infusion, bypassing constricted airways to deliver the drug directly to the lungs. Preclinical studies showed MN-221 to have a high affinity for the beta(2)-adrenergic receptor, found primarily in the lungs, and a much lower affinity for the beta(1)-adrenergic receptor found primarily in cardiac tissue. These studies showed no worrisome increase in heart rate when MN-221 was administered.
News For MNOV From The Last 14 Days
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October 23, 2014
19:04 EDTMNOVMediciNova says CDC supports recruitment for clinical trial of MN-166
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October 22, 2014
19:01 EDTMNOVMediciNova confirmsFDA granted orphan drug designation to MN-001
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07:28 EDTMNOVNortheast Amyotrophic Lateral Sclerosis Consortium to hold annual meeting
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October 21, 2014
18:05 EDTMNOVMediciNova granted orphan status for idiopathic pulmonary fibrosis drug
The FDA posted on its website that MediciNova has been granted orphan status for its treatment of idiopathic pulmonary fibrosis. Reference Link

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