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November 6, 2012
19:25 EDTMDTMedtronic finds biventricular pacing may offer significant clinical advantage
Medtronic announced interim findings from the BLOCK HF trial, which show that biventricular pacing may offer a significant clinical advantage and improved patient outcomes over conventional right ventricular pacing among patients with left ventricular systolic dysfunction and atrioventricular block who are indicated for a pacemaker. Presented as a late-breaking clinical trial at the American Heart Association's 2012 Scientific Sessions, BLOCK HF shows a 27% relative risk reduction in the composite of death and healthcare utilization visits requiring intravenous heart failure therapy among this patient population. The CRT devices used in the BLOCK HF trial are not approved by the FDA for the patient population studied at this time.
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August 25, 2015
09:07 EDTMDTMedtronic to acquire Twelve for $458M
In support of the company's therapy innovation strategy, Medtronic announced that it has signed a definitive agreement to acquire Twelve, a medical device company focused on the development of a transcatheter mitral valve replacement, or TMVR device. Twelve is the twelfth company spun out from the premier medical device incubator The Foundry. Medtronic has agreed to pay up to $458M for Twelve including $408M at closing and $50M on achievement of CE Marking. The cash- and debt-free transaction remains subject to customary closing conditions, and is expected to close in October 2015.

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