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May 12, 2014
08:04 EDTLGNDLigand earns milestone from SAGE Therapeutics for SAGE-547
Ligand Pharmaceuticals announced that it has earned a $150,000 milestone payment from SAGE Therapeutics relating to the earlier commencement by SAGE of a Phase 1/2 clinical trial of SAGE-547 for the treatment of super-refractory status epilepticus, a life-threatening seizure condition in which the brain is in a state of persistent seizure. SAGE-547 is an intravenous agent in Phase 1/2 clinical development as an adjunctive therapy, a therapy combined with current therapeutic approaches, for the treatment of SRSE. SAGE utilizes Ligand’s Captisol technology to develop SAGE-547 for status epilepticus and traumatic brain injury. In 2013, Ligand entered into a platform license agreement with SAGE for the development and commercialization of Captisol-enabled therapeutics for a broad range of debilitating central nervous system conditions. Elements of that agreement were also recently expanded to cover additional therapy areas for certain compounds.
News For LGND From The Last 14 Days
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April 23, 2015
16:14 EDTLGNDLigand names Melanie Herman Interim CFO
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April 22, 2015
12:01 EDTLGNDLigand earns milestone payment from Sage Therapeutics for SAGE-547
Ligand (LGND) announced that it has earned a $500,000 milestone payment from SAGE Therapeutics (SAGE) relating to the treatment of the first patient in SAGE’s Phase 3 open-label expanded access protocol, designated Study 302. Study 302 is designed to offer SAGE-547 to patients affected by super-refractory status epilepticus and to evaluate the safety of SAGE-547 in patients with SRSE. SAGE has reported that the results from this clinical trial, along with results from SAGE's planned Phase 3 placebo-controlled clinical trial - called the STATUS Trial – and other clinical data obtained from the SAGE-547 development program are intended to form the basis of a New Drug Application submission.
April 21, 2015
09:16 EDTLGNDTG Therapeutics data positive, says Roth Capital
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April 20, 2015
07:41 EDTLGNDLigand partner TG Therapeutics presents pre-clinical data on IRAK4 compounds
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April 15, 2015
07:41 EDTLGNDEBD Group to hold a forum
ChinaBio Partnering Forum 2015 is being held in Shanghai, China on April 15-16.

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