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News Breaks
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November 20, 2009
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| 08:02 EDT |  | LGND |
| theflyonthewall.com: | Ligand Pharmaceuticals announces positive data from study on LGD-4033 | | Ligand Pharmaceuticals announced that data from a preclinical study on its selective androgen receptor modulator, or SARM, LGD-4033 was featured in a poster presentation at the 62nd Annual Meeting of the Gerontology Society of America in Atlanta. LGD-4033 exhibited desirable in vivo efficacy on skeletal muscle and bone measurements in animal models of male hypogonadism and postmenopausal osteoporosis. :theflyonthewall.com |
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News For LGND From The Last 14 Days Check below for free stories on LGND the last two weeks.
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February 7, 2012
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| 16:19 EDT | | LGND |
| | 16:17 EDT |  | LGND |
| | 16:16 EDT | | LGND |
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February 2, 2012
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| 06:00 EDT | | LGND |
| theflyonthewall.com: | Ligand Pharmaceuticals' Melphalan shows succesful results in Phase II trial | | Ligand Pharmaceuticals (LGND) provided results from the Phase II study of its Captisol-enabled, propylene glycol-free Melphalan program. The Phase II study was completed in late 2011 and compared the safety, tolerability and pharmacokinetic profiles of the PG-free Melphalan intravenous formulation and the current clinically-used intravenous formulation of melphalan, sold by GlaxoSmithKline (GSK) as Alkeran for Injection, for multiple myeloma patients undergoing autologous transplantation. The Captisol-enabled product is expected to allow for longer administration durations and slower infusion rates, potentially enabling a higher dose intensity of pre-transplant chemotherapy. The new PG-free Melphalan was bioequivalent to Alkeran per guidance requirements, while also demonstrating a marginally higher systemic drug exposure of the multiple myeloma patients. Based on the successful Phase II results, the follow-on Pivotal study will utilize a dosing regimen comparable to Alkeran. :theflyonthewall.com |
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