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News Breaks
May 10, 2013
11:48 EDTJNJ, AZN, GSK, LLY, SNY, RHHBY, MRK, BMY, PFEDrugmakers to face pressure on U.S. prices, Reuters says
Big pharmaceutical companies have enjoyed higher a premium on their drugs in the U.S. market when compared to Europe, but a report from Reuters says that President Obama's health reform bill will put downward pressure on drug prices over the next three to five years. Reference Link
News For JNJ;AZN;GSK;LLY;SNY;RHHBY;MRK;BMY;PFE From The Last 14 Days
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April 6, 2014
13:57 EDTLLYLilly to present data from bemaciclib as potential treatment for breast cancer
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13:46 EDTPFEPfizer's palbociclib significantly prolonged PFS in metastatic breast cancer
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13:37 EDTMRKMerck presents findings on clinical outcomes following treatment with MK-3475
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April 4, 2014
08:07 EDTMRKMerck, Ferring announce collaboration with WHO
Merck and Ferring Pharmaceuticals announced their collaboration with the World Health Organization to advance a new, proprietary formulation of carbetocin, used to prevent excessive bleeding in women after childbirth, that is designed to be stable at room temperature, even in hot and tropical climates. Currently, oxytocin, the standard medicine administered for the prevention of excessive bleeding, is temperature-sensitive and requires sustained cold distribution and storage in hot climates. The WHO will conduct a multi-country clinical study to evaluate the effectiveness of room-temperature-stable carbetocin, as compared to oxytocin. The development of a medicine that can be stored at room temperature has the potential to significantly improve management of bleeding following childbirth in the many areas of the world where cold storage is difficult to achieve and maintain, and thereby help reduce maternal deaths in those areas. Starting this year, the study will take place in 12 countries around the world and enroll approximately 29,000 women. If the results of the study are positive, the organizations will work together with the aim of making the medicine available in developing countries that have a high burden of maternal mortality at an affordable and sustainable public-sector price.
06:29 EDTGSKGlaxoSmithKline cuts China employees amid probe, WSJ reports
According to a source, as it deals with a bribery probe in Beijing, GlaxoSmithKline is cutting employees in China, the Wall Street Journal reports. It is unclear how many of Glaxo's 7,000 employees in China have been let go. Reference Link
April 3, 2014
10:03 EDTRHHBYRoche unit signs companion diagnostic agreement with Genmab
Ventana Medical Systems, a member of the Roche Group, announced that it has entered into an agreement with Genmab A/S for the development of companion diagnostic tools for Genmab's HuMax-TF-ADC antibody drug conjugate program. The TF assay will be developed for possible designation as the screening test in clinical trials involving HuMax-TF-ADC.
10:00 EDTLLYOn The Fly: Analyst Upgrade Summary
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09:37 EDTGSKAmgen to pay GlaxoSmithKline $275M to terminate denosumab collaboration pact
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09:30 EDTPFEApple, Pfizer others create 'go slow' patent lobby group, Reuters says
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08:51 EDTLLYEli Lilly upgraded at Cowen
As reported previously, Cowen raised its rating on Eli Lilly to Outperform from Neutral. The firm cited its Alimta patent victory, margin expansion potential, and late stage pipeline catalysts for the upgrade. Price target raised to $68 from $61.
08:27 EDTLLY, PFELeerink's biotech analyst holds a dinner meeting update
Biotech Analyst Liang holds an update from the AACR's Annual Meeting to discuss some of the presentations including PFE/AMGN's Palbociclib, PBYI/PFE's Neratinib, as well as other new agents for breast cancer from LLY, MDVN and CLDX, in San Diego on April 7 at 9 pm.
06:36 EDTSNYSanofi on lookout for acquisitions, expects growth in Africa, Reuters says
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06:33 EDTLLYEli Lilly upgraded to Outperform from Market Perform at Cowen
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05:50 EDTPFEStocks with implied volatility movement; OXY PFE
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April 2, 2014
11:55 EDTPFEUniqure rises after Baxter acquires Chatham Therapeutics
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09:18 EDTGSKOn The Fly: Pre-market Movers
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08:40 EDTJNJPiper Jaffray to hold booth tours
Booth Tours at SAGES Annual Meeting will be held in Salt Lake City, Utah on April 2-3.
07:44 EDTGSKAgenus down 9.4% after GlaxoSmithKline stops MAGRITi Phase 3 trial
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06:11 EDTGSKGlaxoSmithKline confirms plans to stop MAGRIT Phase III trial
GlaxoSmithKline announced its decision to stop the MAGRITi trial, a Phase III trial of its MAGE-A3ii cancer immunotherapeuticiii in non-small cell lung cancer patients, after establishing that it will not be possible to identify a sub-population of gene-signature positive NSCLC patients that may benefit from the treatment. Data from the trial announced on 20 March 2014 showed that it did not meet its first or second co-primary endpoints as it did not significantly extend disease-free survival when compared to placebo in either the overall MAGE-A3 positive population or in those MAGE-A3-positive patients who did not receive chemotherapy. The trial will be stopped and GSK will now gain access to the un-blinded data, in order to conduct a full assessment of the findings and understand learnings for other aspects of immunotherapy development within GSK. The Independent Data Monitoring Committee indicated that its review of the current safety information revealed no specific safety concern and the data is in line with the known safety information for the MAGE-A3 cancer immunotherapeutic.
05:45 EDTGSKAgenus announces GSK's MAGE-A3 Phase 3 study will be stopped
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