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June 19, 2014
07:54 EDTISISNEJM publishes study on loss-of-function mutations in APOC3
An article in the New England Journal of Medicine concluded, "Rare mutations that disrupt APOC3 function were associated with lower levels of plasma triglycerides and APOC3. Carriers of these mutations were found to have a reduced risk of coronary heart disease." Isis Pharmaceuticals is advancing an APOC3 antisense program into Phase 3, says Piper Jaffray. The firm believes the NEJM article further supports a role for the product beyond the pancreatitis-lowering benefit. Reference Link]:[http://www.nejm.org/doi/full/10.1056/NEJMoa1307095?query=featured_home]
News For ISIS From The Last 14 Days
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August 28, 2014
07:05 EDTISISIsis Pharmaceuticals initiates ISIS-APOCIII Phase 3 study
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August 22, 2014
12:39 EDTISISThese five companies will benefit from increased ALS awareness, MarketWatch says
A recent surge in funding for Lou Gehrig's disease, or ALS, caused by the Ice Bucket challenge that is widespread on social media outlets, will benefit five pharmaceutical companies that are involved in the development of a cure for ALS, according to MarketWatch. The companies that are or have been involved in developing a treatment for ALS include Biogen Idec (BIIB), Avanir Pharmaceuticals (AVNR), Isis Pharmaceuticals (ISIS), Sanofi (SNY), and Bristol-Myers Squibb (BMY), MarketWatch added. Reference Link

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