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News Breaks
May 2, 2014
07:09 EDTISISIsis Pharmaceuticals reports final Phase 2 data on ISIS-APOCIIIRx
Isis Pharmaceuticals announced the final data from its Phase 2 study of ISIS-APOCIIIRx as a monotherapy in patients with familial chylomicronemia syndrome, or FCS. In this open-label study, three patients with FCS treated with ISIS-APOCIIIRx achieved substantial reductions in triglycerides with all three patients achieving a triglyceride level below 500 mg/dL, which substantially reduces the risk of an acute pancreatitis event. In addition, significant reductions in chylomicrons were observed that correlated with reductions in triglyceride levels.
News For ISIS From The Last 14 Days
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November 20, 2014
07:24 EDTISISGoldman to hold a conference
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06:40 EDTISISIsis Pharmaceuticals price target raised to $62 from $53 at Piper Jaffray
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November 18, 2014
15:48 EDTISISGenzyme, Isis present KYNAMRO data at AHA meeting
Genzyme, a Sanofi (SNY) company, and Isis Pharmaceuticals (ISIS) announced that new two-year data from a phase 3 long-term extension study of KYNAMRO injection was presented at a scientific session at the annual American Heart Association meeting. In the study, a retrospective analysis showed that patients treated with KYNAMRO for a mean of two years had a significant reduction in Major Adverse Cardiovascular Events compared to two years prior to therapy. The rate of MACE in patients treated with KYNAMRO for two years were adjudicated by an independent committee and compared to the rate of MACE in the same patients based on their medical history prior to treatment with KYNAMRO. In this analysis, MACE were identified in 62% of patients during two years prior to KYNAMRO treatment, and 9% of patients during a mean of 24.4 months after initiation of treatment with KYNAMRO.
November 14, 2014
15:41 EDTISISIsis Pharmaceuticals management to meet with Piper Jaffray
Meeting to be held in Kansas City, MO on November 18 hosted by Piper Jaffray.
November 13, 2014
05:34 EDTISISAstraZeneca, Isis Pharmaceuticals to co-develop oligonucleotide delivery methods
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November 12, 2014
07:53 EDTISISLeerink to hold a tour
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November 10, 2014
16:07 EDTISISIsis Pharmaceuticals files to sell $425M in convertible senior notes due 2021
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November 7, 2014
08:33 EDTISISIsis Pharmaceuticals reports Q3 EPS (23c), consensus (20c)
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November 6, 2014
15:27 EDTISISNotable companies reporting before tomorrow's open
Notable companies reporting before tomorrow's market open, with earnings consensus, include Humana (HUM), consensus $2.00; Brookfield Asset Management (BAM), one estimate 33c; Magnum Hunter (MHR), consensus (16c); Cooper Tire & Rubber (CTB), consensus 72c; E. W. Scripps (SSP), consensus 6c; Isis Pharmaceuticals (ISIS), consensus (20c); ViaSat (VSAT), consensus 15c; Dresser-Rand (DRC), consensus 63c; Intercept Pharmaceuticals (ICPT), consensus ($1.10).
07:43 EDTISISIsis Pharmaceuticals earns $10M milestone payment from Biogen
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