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Stock Market & Financial Investment News

News Breaks
April 30, 2014
07:29 EDTISISIsis Pharmaceuticals price target lowered to $55 from $63 at Stifel
Stifel cut its price target on ISIS after updated P2 ISIS-SMNRx data in Type-1 spinal muscular atrophy showed two patients in the trial experienced an event. The firm is not surprised by this development but believes it reinforces the risk of conducting such trials. Stifel keeps a Buy rating on the shares.
News For ISIS From The Last 14 Days
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July 17, 2014
07:10 EDTISISIsis Pharmaceuticals begins Phase 2 study of candidate for high lipoprotein(a)
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July 16, 2014
07:14 EDTISISIsis Pharmaceuticals earns $1M milestone payment from GlaxoSmithKline
Isis Pharmaceuticals (ISIS) has earned a $1M milestone payment from GlaxoSmithKline (GSK) related to the advancement of the Phase 2/3 study of ISIS-TTRRx in patients with familial amyloid polyneuropathy. ISIS-TTRRx is an antisense drug in development with GSK for the treatment of transthyretin amyloidosis, a severe and rare genetic disease characterized by progressive dysfunction of peripheral nerve and/or heart tissues. Including this milestone payment, Isis has generated $27M in upfront and milestone payments for advancing ISIS-TTRRx. If GSK elects to exercise its option to exclusively license the ISIS-TTRRx program, Isis is eligible to receive a license fee, regulatory and sales milestone payments and double-digit royalties on sales of ISIS-TTRRx.

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