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May 14, 2014
05:38 EDTINCY, AZNIncyte, MedImmune collaborate on immuno-oncology combination clinical trial
Incyte (INCY) and MedImmune, the global biologics research and development arm of AstraZeneca (AZN), announced that they have entered into a clinical study collaboration. The Phase I/II oncology study will evaluate the efficacy and safety of MedImmune’s investigational anti-PD-L1 immune checkpoint inhibitor, MEDI4736, in combination with Incyte’s oral indoleamine dioxygenase-1 inhibitor, INCB24360. Under the terms of the agreement, MedImmune and Incyte will collaborate on a non-exclusive basis on the study, to evaluate the combination in multiple solid tumors including metastatic melanoma, non-small cell lung cancer, squamous cell carcinoma of the head and neck and pancreatic cancer. The Phase I part of the trial is expected to establish a recommended dose regimen of both MEDI4736 and INCB24360 and the Phase II part of the study will assess the safety and efficacy of the combination. Results from the study will be used to determine whether further clinical development of this combination is warranted. The study will be co-funded equally by Incyte and MedImmune and conducted by Incyte.
News For INCY;AZN From The Last 14 Days
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January 29, 2015
06:55 EDTAZNAstraZeneca announces four research collaborations for CRISPR
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January 28, 2015
17:06 EDTINCYIncyte publish Phase III RESPONSE trial results for polycythemia vera patients
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08:10 EDTINCYIncyte receives orphan status for pancreatic cancer treatment
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07:39 EDTAZNPfizer CEO says company not in need of big M&A deal, FT reports
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January 27, 2015
12:54 EDTAZNBox, Inc. lands AstraZeneca contract to service 51,000 users, Re/code reports
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January 26, 2015
15:24 EDTAZNTeva confirms U.S. approval of AstraZeneca's Nexium generic
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January 23, 2015
07:36 EDTINCYIncyte earns $25M milestone payment from Novartis for Jakavi
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January 21, 2015
12:30 EDTAZNGlaxoSmithKline 'admired' by Pfizer CEO, FT reports
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10:16 EDTAZNLeerink biopharma analysts hold an analyst/industry conference call
Analyst Fernandez, along with Dr. Paul Gurbel and Dr. Richard Becker, discuss AstraZeneca's PEGASUS trial and the current use of Brilinta and dual antiplatelet therapy for prevention of CV disease and implications of the recently completed DAPT trial on an Analyst/Industry conference call to be held on January 21 at 1:30 pm.

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