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March 28, 2014
07:16 EDTIDRAIdera Pharmaceuticals says Phase 2 trial of IMO-8400 met primary endpoint
Idera Pharmaceuticals announced positive top-line data from its randomized, double-blind, placebo controlled Phase 2 trial of IMO-8400 in 32 patients with moderate-to-severe plaque psoriasis. The primary objective of the trial was to evaluate the safety and tolerability of IMO-8400 over a 12-week treatment period, with a secondary objective to evaluate the clinical activity of IMO-8400. The trial met its primary objective as all treatments were well tolerated with no treatment related discontinuation, serious adverse events or dose reductions. IMO-8400 treatment met the secondary objective of demonstrating clinical activity in patients with psoriasis, as assessed by Psoriasis Area and Severity Index. IMO-8400, which is Idera’s lead clinical candidate, is an antagonist of Toll-like receptors 7, 8, and 9. Idera’s strategy is to develop IMO-8400 for the treatment of genetically defined forms of B-cell lymphoma and orphan autoimmune diseases.
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November 18, 2014
07:37 EDTIDRAStifel to hold a conference
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