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February 7, 2014
14:50 EDTNEON, IDRA, OUTR, PHHHigh option volume stocks: IDRA PHH VI NEON OUTR
News For IDRA;PHH;OUTR;NEON From The Last 14 Days
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April 10, 2014
16:37 EDTOUTRJana Partners cuts stake in Outerwall to 4.9% from 8.4%
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April 7, 2014
16:13 EDTIDRAIdera says preclinical data shows inhibition of lymphoma cells
Idera Pharmaceuticals presented new preclinical data demonstrating the ability of its Toll-like receptor antagonist, IMO-8400, to inhibit the survival and proliferation of B-cell lymphoma cells harboring the oncogenic MYD88 L265P genetic mutation. These data add to the research which supports the company’s efforts to develop IMO-8400 for the treatment of genetically defined forms of B-cell lymphoma. The data build upon reports from independent investigators and provide additional evidence that the MYD88 L265P mutation, which is present in certain B-cell lymphomas, results in over-activation of TLR7 and TLR9 mediated signaling. Idera has opened enrollment in a Phase 1/2 trial of IMO-8400 designed to evaluate IMO-8400’s safety, tolerability and potential clinical activity in patients with Waldenstrom’s macroglobulinemia who are refractory to prior therapies. The company anticipates that patient treatment in this trial will begin in Q2. Idera has also submitted a separate protocol to the U.S. FDA to conduct a Phase 1/2 trial in patients with DLBCL who harbor the MYD88 L265P mutation.
09:21 EDTOUTROuterwall Q2 revenue guidance could miss consensus, says Northland Securities
Northland Securities believes that Outerwall's Q2 sales guidance could be conservative and below consensus, as the firm thinks that Q2 is on track to be one of the weakest quarters for domestic box office revenue in a few years. The firm expects Redbox's performance in Q1 to be solid, however. It keeps a $75 price target and Market Perform rating on the shares.

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