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May 20, 2014
17:02 EDTGHDXGenomic Health announces data reinforcing robustness of Oncotype DX
Genomic Health presented positive results reinforcing the robustness of the Oncotype DX prostate cancer test's development as a predictor of prostate cancer aggressiveness. A sub-analysis of a large Oncotype DX Genomic Prostate Score, or GPS, development study suggests that GPS predicts time to clinical progression regardless of the treatment received following surgery. This exploratory analysis from one of the original development studies looked at a subset of 185 prostate cancer patients who experienced biochemical recurrence after surgery. These patients were analyzed in three subgroups based on treatment received at time of biochemical recurrence: men who did not receive additional treatment, men who received hormonal therapy and men who received radiation therapy. Results showed that the Oncotype DX Genomic Prostate Score was predictive of clinical recurrence for all patients, regardless of the type of treatment patients received. For each therapy subgroup, different biological pathways within the GPS were most highly associated with patient outcome.
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April 30, 2015
08:10 EDTGHDXGenomic Health's Oncotype prostate cancer shows positive results
Genomic Health announced positive published results from the first decision impact study of the Oncotype DX prostate cancer test showing that use of the test substantially increased the number of men who can consider active surveillance, while increasing physician confidence in their treatment recommendations. This prospective study showed that incorporation of the Genomic Prostate Score changed modality and/or intensity of treatment recommendations in 26% of patients across multiple urology practice settings. Additionally, 85% of urologists were more confident in their treatment recommendation following review of the GPS.

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