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November 12, 2012
08:01 EDTGALTGalectin Therapeutics presents preclinical data on GR-MD-02
Galectin Therapeutics presented new preclinical data on the mechanism of action of GR-MD-02 at the American Association for the Study of Liver Disease Annual Meeting in Boston, MA. GR-MD-02 is the Company’s lead galectin inhibitor in development for the treatment of non-alcoholic steatohepatitis, or fatty liver disease. These new data help to further explain the mechanism of action of GR-MD-02, showing that this galectin inhibitor affects multiple pathways involved with both the prevention and reversal of fibrosis in NASH pathology. The new data show that Galectin-3 protein expression was markedly increased in animals with NASH, and those levels were dramatically reduced to barely detectable levels following treatment with GR-MD-02. Elevated expression of iNOS, an important inflammatory mediator, and CD36, a scavenger receptor involved in the pathogenesis of NASH, were markedly reduced following treatment with GR-MD-02.
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September 15, 2014
08:07 EDTGALTGalectin Therapeutics issued U.S. patent for GR-MD-02
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September 12, 2014
15:12 EDTGALTGalectin Therapeutics says in ongoing talks with large pharma companies
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September 11, 2014
07:25 EDTGALTAegis to hold a conference
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