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News Breaks
June 2, 2014
07:14 EDTGALEGalena presents GALE-301 Phase 1 data
Galena announced that data from the company's Phase 1 study with GALE-301, or Folate Binding Protein, was presented at the American Society of Clinical Oncology 50th Annual Meeting. The poster entitled, "Comparison of recurrent and nonrecurrent ovarian and uterine cancer patients undergoing adjuvant folate receptor vaccine therapy," was presented during the Gynecologic Cancer General Poster Session. Overall, 30 patients were enrolled in the Phase 1 trial. Of 14 control patients, 50% have recurred. Of 16 vaccinated patients, 25% have recurred after completing the primary vaccine series and 12.5% recurred prior to completing the PVS, and one patient withdrew. Of note, no recurrences have been seen in the optimal dose cohort of 1000 mcg E39. The vR patients displayed lower mean delayed type hypersensitivity reactions as well as lower local reactions at every measured time point. The company said, "These promising initial results demonstrate the vaccine is dose responsive with the immune system and we are encouraged about the potential for this compound to prevent recurrence in women suffering from high risk gynecological cancers where current treatment options are limited. The data from this study served as the basis for advancing GALE-301 into its ongoing Phase 2 trial that includes a booster regimen. We expect enrollment in this trial to complete shortly, ahead of schedule."
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August 21, 2014
07:15 EDTGALEGalena announces resignation of CEO Mark Ahn
Galena Biopharma announced that Mark Schwartz, Ph.D., has been appointed as President and CEO, effective immediately. Dr. Schwartz was previously Galena's COO. He replaces Mark Ahn, Ph.D. who has resigned as the President and CEO and as a director of the company to pursue "other long held personal and professional goals." It is expected that Dr. Schwartz will also be appointed to Galena's board.
05:32 EDTGALEGalena fired CEO over stock promotion scandal, Feuerstein says
Galena fired its CEO Mark Ahn following a stock promotion scandal, The Street's Adam Feuerstein reported last night, citing a source close to the company. A public announcement is coming today, Feuerstein added.

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