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April 12, 2014
19:23 EDTENTA, ABBVEnanta reports detailed results from Turquoise ll study
Enanta Pharmaceuticals (ENTA) announced that detailed results from AbbVie’s (ABBV) pivotal phase 3 TURQUOISE-II study, will be presented as a late-breaking oral presentation at the International Liver Congress, ILC, which is the 49th Annual Meeting of the European Association for the Study of the Liver, EASL. Results from the TURQUOISE-II study were featured in the ILC press conference and were published on-line in the New England Journal of Medicine. The TURQUOISE-II study reports results from AbbVie’s investigational three direct-acting antiviral regimen containing ABT-450, Enanta’s lead protease inhibitor discovered through Enanta’s collaboration with AbbVie. The regimen consists of boosted protease inhibitor ABT-450/ritonavir, NS5A inhibitor ABT-267, and non-nucleoside polymerase inhibitor ABT-333. TURQUOISE-II is a global, multi-center, randomized, open-label study evaluating the efficacy and safety of 12 weeks or 24 weeks of treatment with AbbVie's three direct-acting antiviral regimen with ribavirin, RBV, in adult patients with genotype 1, GT1, chronic hepatitis C virus, HCV, infection with compensated liver cirrhosis. Patients achieved sustained virologic response rates 12 weeks post-treatment, SVR12, of 91.8% and 95.9% in the 12-week and 24-week treatment arms, respectively. Patients in the study were either new to therapy or treatment-experienced, failed previous treatment with pegylated interferon and RBV.
News For ENTA;ABBV From The Last 14 Days
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June 30, 2015
07:33 EDTENTAEnanta appoints Nathalie Adda as SVP, chief medical officer
Enanta Pharmaceuticals (ENTA) announced the appointment of Nathalie Adda, M.D., as senior VP and chief medical officer, responsible for clinical and regulatory affairs. Most recently, Adda was chief medical officer, VP Clinical Development, Medical and Regulatory Affairs at Transgene (TRNG), where she led the Oncology and Infectious Disease programs since 2012.
07:32 EDTABBVJuno pact leaves Celgene set for growth past Revlimid, says Deutsche Bank
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June 26, 2015
12:02 EDTABBVEMA adopts positive opinion on AbbVie's Humira for acne inversa
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June 24, 2015
06:12 EDTABBVAbbVie announces new TURQUOISE-III study results
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June 22, 2015
08:56 EDTENTAEnanta management to meet with JPMorgan
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