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May 30, 2014
08:36 EDTDXRHeart failure study from Mayo Clinic using Daxor's BVA-100 published
The Journal of the American College of Cardiology - Heart Failure has published the first study measuring congestive heart failure patients' blood volumes at the initiation of treatment and just prior to discharge. This study involved 26 Class III/IV cardiac patients who are usually treated without blood volume measurements on the basis of clinical evaluations and tests such as hematocrits/hemoglobins, which measure the ratio of a patient's red cells but not the actual volume of a patient's blood. Retention of sodium and water and expansion of a patient's blood volume are the most fundamental derangements which occur in congestive heart failure patients. Total blood volume analysis demonstrates a wide range in the extent of volume overload. 24 out of 26 patients were hypervolemic, with a range of up 9.5%-107% above the normal volume. By measuring blood volume at discharge, it was possible to compute whether the fluids removed were from the blood volume itself or from the interstitial fluid, which is the body fluid surrounding the cells of the body. On average 85% of the fluid removed came from the interstitial space. However, there was a wide range of variability within the patient population. The authors also noted that at discharge, despite vigorous therapy, most of the patients still had abnormally expanded blood volumes. The authors noted "The extent of composition and distribution of volume overload are highly variable in decompensated congestive heart failure and this variability needs to be taken into account in the approach to individualized therapy. The authors further noted that "Utilizing current methods, the accurate assessment and management of volume overload in patients with decompensated heart failure remains problematic".
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December 11, 2014
08:43 EDTDXRDaxor announces major study with Mayo Clinic
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