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March 24, 2014
08:04 EDTCYTXCytori says study using therapy to treat ACL injury underway in Spain
Cytori Therapeutics announces the first investigator-initiated study evaluating Cytori Cell Therapy as a potential concomitant treatment for Anterior-cruciate ligament injury. The study is led by Ramon Cugat, M.D. PhD. Dr. Cugat is President of the Medical Council for the Catalan Soccer Delegation's Health Insurance Company under the Spanish Soccer Federation, President of the Board of Directors of the Council of the Garcia Cugat Foundation for Regenerative Medicine Research, Professor of the Chair of the Garcia Cugat Foundation at CEU Cardenal Herrera University, Director of the Orthopaedic Surgical Department in Hospital Quiron, Barcelona, Spain and Head of Trauma and Orthopaedic Surgery in Mutua Patronal Montañesa. The study is an investigator-initiated study to determine the feasibility of using Cytori Cell Therapy on patients undergoing complete ACL reconstruction. The study is approved to treat 20 patients who will be followed by both clinical and imaging end points. Thirteen patients have been treated thus far, full enrollment is expected this year and data is being evaluated on a rolling basis. The study was initiated in 2013 under an approval from the Spain Ministry of Health, Social Services and Equality. It was organized by a multidisciplinary team of researchers at Hospital Quiron.
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November 21, 2014
09:17 EDTCYTXOn The Fly: Pre-market Movers
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08:03 EDTCYTXCytori Therapeutics announces results in Cytori Cell Therapy trial
Cytori Therapeuticsreported positive results from a clinical study of Cytori Cell Therapy in anterior cruciate ligament reconstruction of patients with ACL tears. The 6 month results from the first 20 patients with combination Cytori Cell Therapy and bone-patellar tendon-bone grafts were presented at the Barcelona Knee Symposium on November 20, 2014. Dr. Ramon Cugat, co-director of the Orthopedic Institute, Hospital Quiron Barcelona and the lead investigator of the study, performed autologous bone-patellar tendon-bone transplantation to replace damaged ACLs in 20 athletes who had sustained injury. Cytori Cell Therapy utilizing adipose derived regenerative cells prepared by the Celution System from a patient’s own fat was used with the BPTB graft during the transplantation procedure. The cell preparation, injection into the graft and transplantation of the graft were all performed in the same surgical procedure. Dr. Cugat discussed the preliminary six month outcomes at the meeting. The procedure was feasible and not associated with safety issues above that seen with a standard small volume liposuction. All patients recovered without any complications. The results were compared to a historical control group of patients who had the same surgical procedure by the same surgical team but without other interventions. Overall, recovery from pain and ability to return to the field appeared to be accelerated as a result of the ADRC enriched BPTB transplant The patient questionnaires and serial MRI scans of the knees following cell therapy were consistent with accelerated healing of the graft.
November 18, 2014
11:04 EDTCYTXCytori Therapeutics announces early results from ADVANCE trial
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