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December 7, 2012
07:36 EDTCYTKCytokinetics presents analyses from Tirasemtiv clinical trials in ALS patients
Cytokinetics announced a platform presentation of pharmacokinetic data and pharmacokinetic/pharmacodynamic analyses from three previously-reported clinical trials of tirasemtiv in patients with amyotrophic lateral sclerosis, or ALS, at the 23rd International Symposium on ALS and Motor Neurone Diseases, or ALS/MND, in Chicago, IL. Tirasemtiv selectively activates the fast skeletal muscle troponin complex by increasing its sensitivity to calcium, which increases skeletal muscle force in response to neuronal input. In preclinical studies, this mechanism has been shown to delay the onset and reduce the degree of muscle fatigue. Tirasemtiv is currently being evaluated in BENEFIT-ALS, an international, double-blind, randomized, placebo- controlled, Phase IIb clinical trial designed to evaluate the safety, tolerability and potential efficacy of this novel drug candidate in patients with ALS.
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April 23, 2014
09:13 EDTCYTKCytokinetics should be owned ahead of data, says Roth Capital
Roth Capital recommends that investors own Cytokinetics ahead of data expected to be unveiled on April 29. The firm thinks the data could be "a transformational event" for the company, and reiterates a $25 price target and Buy rating on the shares.
April 21, 2014
10:58 EDTCYTKCytokinetics mentioned positively at Piper Jaffray
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April 16, 2014
14:33 EDTCYTKCytokinetics volatility elevated into trial data announcement
Cytokinetics May call option implied volatility is at 279, August is at 180, November is at 140; compared to its 26-week average of 158 according to Track Data, suggesting larger near term price movement into the tirasemtiv Phase IIb trial data likely to be announced at the American Academy of Neurology meeting in late April.
April 11, 2014
10:56 EDTCYTKOptions with increasing implied volatility: CYTK VJET DATA GRPN CTRP
April 10, 2014
11:23 EDTCYTKOptions with increasing implied volatility: CYTK BX
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