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News Breaks | | | | January 9, 2013 | | 05:25 EDT |  | CTIC | Cell Therapeutics begins enrollment in Phase 3 trial of Pacritinib
Cell Therapeutics announced that the company has initiated clinical trial sites and began enrolling patients in a Phase 3 clinical trial, known as PERSIST-1 or PAC325, for pacritinib, CTI's investigational JAK2 inhibitor, which is being evaluated for the treatment of patients with myelofibrosis. The randomized trial is expected to enroll 270 patients and will evaluate the safety and efficacy of pacritinib compared to best available therapy, excluding JAK inhibitors, in patients with myelofibrosis. Pacritinib is a selective oral JAK2 inhibitor that demonstrated meaningful clinical benefits and good tolerability in myelofibrosis patients in Phase 2 clinical trials, without apparent drug-related thrombocytopenia or anemia. Myelofibrosis patients will be enrolled in the PERSIST-1 trial without exclusion for low platelet counts. | |
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News For CTIC From The Last 14 Days Check below for free stories on CTIC the last two weeks. |
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| May 20, 2013 | | 05:47 EDT | | CTIC | Cell Therapeutics reports the G-BA issues final assessment report for Pixuvri
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