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February 13, 2014
07:53 EDTCRMECardiome's Brinavess shows positive results in cardiological study
Cardiome announced that an independent, investigator-led investigation demonstrated real-world cardioversion experience with Brinavess RINAVESS (vernakalant IV) in patients who developed post-cardiac surgery atrial fibrillation. This was a prospective, non-randomised, single-arm study in 50 patients. The primary outcome was the conversion of atrial fibrillation to sinus rhythm 90 minutes post-Brinavess RINAVESS infusion. Brinavess was successful in cardioverting 74% of the patients.
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December 19, 2014
08:24 EDTCRMECardiome enters development, commercialization agreement with Eddingpharm
Cardiome Pharma announced that one of its subsidiaries has entered into an agreement with Eddingpharm to develop and commercialize BRINAVESS in China, Taiwan, and Macau and re-launch BRINAVESS in Hong Kong. Eddingpharm will be responsible for any clinical trials and regulatory approvals required to commercialize BRINAVESS in the countries covered by the agreement. Under the terms of the agreement, Eddingpharm has agreed to an upfront payment of $1.0M and specific annual commercial goals for BRINAVESS. Cardiome is also eligible to receive regulatory milestone payments of up to $3.0M. Other financial details have not been disclosed.

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