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News Breaks
October 17, 2012
08:04 EDTCRL, AZNCharles River Labs announces strategic partnership with AstraZeneca
Charles River Laboratories International (CRL) has been selected by AstraZeneca (AZN) as its preferred strategic partner for outsourced regulated safety assessment and development DMPK. The three-year agreement extends into 2015. AstraZeneca began the process of transferring programs to Charles River earlier this year. This process is expected to be completed by early 2013. In 2013, the incremental sales under this agreement are expected to contribute approximately 1% to Charles River’s total net sales.
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May 21, 2013
09:29 EDTAZNAstraZeneca says Phase III studies of Naloxegol met primary, secondary endpoints
AstraZeneca (AZN) presented the results of two pivotal Phase III studies of naloxegol showing the 25 mg dose of the investigational drug met its primary and secondary endpoints for efficacy and showed a safety profile consistent with previous studies. Data was presented at the Digestive Disease Week meeting in Orlando, Florida. The primary endpoint in both trials was percentage of OIC responders, versus placebo, over 12 weeks of treatment. The secondary endpoints included the 12-week response rate in a laxative inadequate response population, the median time to first spontaneous bowel movement and the number of days per-week with at least one bowel movement. Plans for naloxegol will be finalized over the coming months, incorporating the outcome of ongoing discussions with health authorities in the US, EU and Canada, the company said. Naloxegol, a peripherally-acting mu-opioid receptor antagonist, has been specifically designed for the treatment of opioid-induced constipation and is part of the exclusive worldwide license agreement announced on 21 September 2009, between AstraZeneca and Nektar Therapeutics (NKTR).
May 17, 2013
10:36 EDTAZNLeerink's major/specialty pharma analyst holds analyst/Industry conference call
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08:41 EDTAZNImpax commenced shipment of authorized generic Zomig
Impax (IPXL) announced that its generics division, Global Pharmaceuticals, commenced shipment of authorized generic Zomig tablets, as part of an agreement with AstraZeneca (AZN). Zomig is indicated for the treatment of migraine headaches in adults. According to IMS Health data, U.S. sales of Zomig tablets and orally disintegrating tablets were approximately $196M in the 12 months ended April 2013.
May 14, 2013
07:24 EDTAZNEBD Group to host a conference
BioTrinity 2013 is being held in Newbury, England on May 14-16.
May 13, 2013
16:53 EDTAZNOptimer gets bids from AstraZeneca, Cubist, Astellas, Bloomberg says
Optimer (OPTR) has received first round bids from AstraZeneca (AZN), Cubist (CBST), and Astellas, reports Bloomberg, citing people familiar with the matter. Shares of Optimer spiked higher following the report, closing up $1.85, or 14.44%, to $14.66. The report notes the company disclosed almost three months ago it was exploring its strategic options. Reference Link
15:55 EDTAZNOptimer gets first round bids from AstraZeneca, Cubist, Bloomberg says
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May 10, 2013
11:48 EDTAZNDrugmakers to face pressure on U.S. prices, Reuters says
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May 9, 2013
11:13 EDTCRLPharmaceutical services provider Quintiles surges on first day of trading
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11:11 EDTCRLHigh option volume stocks: DANG DLR CRL MWE AFFY
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10:17 EDTAZNShire trades higher in London amid takeover chatter, Guardian says
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