Covidien completes enrollment in DEFINITIVE AR study As the third study in the DEFINITIVE trial series, this randomized pilot is designed to address the challenge of preventing restenosis, a common occurrence in patients with peripheral artery disease. The DEFINITIVE AR study is designed to evaluate the effect of treating a diseased vessel with a combination therapy that begins with directional atherectomy to remove plaque build-up, followed by the use of a drug-coated balloon that releases anti-proliferative medication to inhibit restenosis.
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