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June 9, 2014
11:50 EDTCGIX, AZNCancer Genetics rises after selection by AstraZeneca unit
Shares of Cancer Genetics (CGIX), an early-stage, diagnostic company that focuses on developing and commercializing genomic tests and services focused on improving cancer care, are higher this morning after the company announced a partnership with AstraZeneca (AZN). WHAT'S NEW: AstraZeneca CAMCAR, a division of the pharmaceutical giant that serves Central American and Caribbean countries, has selected Cancer Genetics to provide diagnostic testing based on biomarkers for cancer. CGI will perform complex testing for diagnosis and prognosis of cancer patients in Central America and the Caribbean. Under the terms of the agreement, CGI will be working closely with AZ-CAMCAR on exploring opportunities to expand into additional geographic territories, more cancer categories and into select oncology trials. This partnership will focus on multiple cancer categories beginning with lung cancer, as the Pan American Health Organization, or PAHO, expects cases the number of new cases and deaths from lung cancer to double in Latin America by 2030. WHAT'S NOTABLE: Cancer Genetics Chief Executive Officer Panna Sharma commented, "We believe our ability to provide accurate, state-of-the-art biomarker-based testing was a key factor in AstraZeneca’s decision to partner with us, and serves as a testament to the growing global awareness of the value of our brand. We are committed to positively impacting cancer care globally, and this relationship serves as another major milestone in fulfilling that mission." PRICE ACTION: Cancer Genetics is trading up 38c, or 3.4%, to $11.58 in late-morning trading.
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July 22, 2014
05:25 EDTAZNAdams Express, MedImmune announce clinical trial partnership
Advaxis (ADXS) has entered into a clinical trial collaboration with MedImmune, the global biologics research and development arm of AstraZeneca (AZN). The Phase I/II immunotherapy study will evaluate the safety and efficacy of MedImmune's investigational anti-PD-L1 immune checkpoint inhibitor, MEDI4736, in combination with Advaxis' lead cancer immunotherapy vaccine, ADXS-HPV, as a treatment for patients with advanced, recurrent or refractory human papillomavirus, or HPV,-associated cervical cancer and HPV-associated head and neck cancer. Both MEDI4736 and ADXS-HPV are cancer immunotherapies, a new class of treatments that use the body's own immune system to help fight cancer. Under the terms of the agreement, MedImmune and Advaxis will evaluate the combination as a treatment for HPV-associated cervical cancer and squamous cell carcinoma of the head and neck. The Phase I part of the trial is expected to establish a recommended dose regimen of MEDI4736 with ADXS-HPV, and the Phase II portion will assess the safety and efficacy of the combination. The study will be funded and conducted by Advaxis. Results from the study will be used to determine whether further clinical development of this combination is warranted. Under the terms of the deal, MedImmune has a non-exclusive relationship with respect to HPV-driven tumour types. MedImmune has first right of negotiation for future development of combinations involving MEDI4736 and ADXS-HPV.
July 21, 2014
07:47 EDTCGIXCancer Genetics to acquire Gentris
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July 16, 2014
10:36 EDTAZNTreasury calls on Congress to halt inversion deals
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08:01 EDTAZNAlexion names former AstraZeneca CEO David Brennan to board
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07:59 EDTAZNTreasury Secretary urges Congress to take action on tax inversions
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07:23 EDTCGIXRedChip Companies to hold a virtual conference
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