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June 11, 2014
07:33 EDTCELGCelgene announces results from long-term Phase III OTEZLA trial
Celgene International Sŕrl, a wholly-owned subsidiary of Celgene Corporation, announced results from a long-term phase III trial of OTEZLA, the company’s oral, selective inhibitor of phosphodiesterase 4, in psoriatic arthritis patients who have not had prior treatment with systemic or biologic disease-modifying antirheumatic drugs. The data were presented at the European League Against Rheumatism Annual Congress in Paris, France. Results demonstrated that treatment with OTEZLA monotherapy in patients with pre-existing enthesitis or dactylitis, two key manifestations of psoriatic arthritis, resulted in long-term improvements. Results were sustained over 52 weeks in patients initially randomized to OTEZLA monotherapy and completing 52 weeks of the study. At week 52, median Maastricht Ankylosing Spondylitis Enthesitis Scoredecreased by 75.0 percent and 45.9 percent of patients receiving OTEZLA 30 mg BID achieved a score of 0, indicating no pain at any of the enthesitis sites assessed. OTEZLA 30 mg BID also resulted in a median 100 percent decrease in dactylitis count. A dactylitis count of 0, indicating no signs of dactylitis, was achieved in 68.8 percent of patients.
News For CELG From The Last 14 Days
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April 24, 2015
10:59 EDTCELGCelgene call activity attributed to vague takeover speculation
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10:22 EDTCELGRumor: Celgene active on vague takeover speculation
Celgene (CELG) shares are active on speculation Bristol-Myers (BMY) may be interested in acquiring the company.
05:39 EDTCELGCelgene announces strategic collaboration with AstraZeneca
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April 23, 2015
17:45 EDTCELGCelgene announces fulfillment of approval requirements for POMALYST
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09:20 EDTCELGCelgene patent latest to be challenged by Hayman Capital's Bass
The Coalition For Affordable Drugs, a group linked to Hayman Capital's Kyle Bass, has requested an Inter Partes Review of Claims 1–10 of U.S. Patent No. 6,045,501 held by Celgene (CELG), according to a USPTO filing. The ’501 patent claims methods for delivering a drug, including a teratogenic drug, to a patient while preventing the exposure of a fetus or other contraindicated individuals to the drug. The patent is related to the company's Revlimid drug. BACKGROUND: Previously, the same coalition requested an Inter Partes Review of patents held by Pharmacyclics (PCYC), Acorda Therapeutics (ACOR), Shire (SHPG) and Jazz Pharmaceuticals (JAZZ). On January 7, Reuters reported that Bass planned to take "around 15 pharmaceutical companies with a combined market capitalization of $450B" into an Inter Partes Review for extending patents in questionable ways, citing a presentation made by Bass in Oslo. PRICE ACTION: Shares of Celgene are down 0.5% to $114.92 in pre-market trading.
April 15, 2015
17:08 EDTCELGCelgene announces phase 2 Apremilast data
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April 13, 2015
09:34 EDTCELGActive equity options trading on open
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05:09 EDTCELGCelgene to purchase 14.35M shares of Mesoblast stock for A$3.82 per share
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April 12, 2015
19:33 EDTCELGCelgene takes stake in Australia's Mesoblast, the Australian says
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