Cellular Biomedicine announces positive Phase I results from CAR-T CD30 trial Cellular Biomedicine Group announced encouraging clinical data from its Chimeric Antigen Receptor, or CAR-T, CD30-positive Hodgkin's lymphoma immuno-oncology clinical development program. The results of this trial to date demonstrated that five out of seven patients responded to the treatment. CD30-directed CAR-T cell therapy was demonstrated in this trial to be safe, feasible and efficient. This trial was a Phase I, open-label trial whereby enrolled patients received escalating doses of autologous T cells transduced with a CD30-directed chimeric antigen receptor moiety for a consecutive 3-5 days. The level of CAR transgenes in peripheral blood and biopsied tumor tissues were measured periodically according to assigned protocol by Quantitative PCR.