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June 19, 2014
08:53 EDTCBMGCellular Biomedicine releases positive ReJoin Phase I/IIa six-month data
Cellular Biomedicine released the six-month follow-up data analysis of its Phase I/IIa clinical trial for its Rejoin human adipose-derived mesenchymal precursor cell, or haMPC, therapy for Knee Osteoarthritis, or KOA. The trial, conducted by Shanghai Renji Hospital, tested the safety and efficacy of intra-articular injections of autologous haMPCs in order to reduce inflammation and repair damaged joint cartilage. The primary endpoints for this trial were safety and knee-related pain, stiffness and function measured using the Western Ontario and McMaster Universities osteoarthritis index questionnaire. The secondary endpoints were cartilage repair at six months, defined through the volume of the repair tissue measured with quantitative magnetic resonance imaging as well as NRS-11, SF-36 and KSCRS scores.
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