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November 27, 2012
07:07 EDTCBLICleveland BioLabs subsidiary signs contract for about $4.6M with Russia
Cleveland BioLabs and Panacela Labs announced award of a contract valued at 146 million rubles, or approximately $4.6M with the Ministry of Industry and Trade of the Russian Federation for development of Xenomycins, a family of compounds in development as anti-infective agents. The contract, issued under the Russian Federation's "Pharma 2020" development initiative, provides matching funding over a period of approximately three years, which will be used to support preclinical and clinical studies.
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February 9, 2016
07:38 EDTCBLICleveland BioLabs says entolimod shown to suppress metastasis
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February 2, 2016
08:15 EDTCBLICleveland BioLabs initiates colorectal cancer study of entolimod in Russia
Cleveland BioLabs announced the initiation of a Phase 2, single-blind, randomized, placebo-controlled clinical study of the safety and tolerability of entolimod as a neo-adjuvant therapy in treatment-naive patients with primary colorectal cancer who are recommended for surgery. The primary objective of the study is to determine the optimal dose and dosing regimen for treatment of these patients with entolimod prior to surgery. Secondary objectives include evaluation of pharmacodynamic parameters, including immune response to single or double administrations of entolimod at varying dose levels. Up to 32 patients are expected to be enrolled in the study, which is being conducted at four leading oncology centers in the Russian Federation. The study is supported by a development contract with the Russian Federation Ministry of Industry and Trade.

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