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June 2, 2014
07:41 EDTBMYBristol-Myers announces follow up results from Study -004
Bristol-Myers Squibb Company announced follow up results from Study -004, a multi-arm Phase 1b dose-ranging trial evaluating the safety and activity of the combination regimen of nivolumab, an investigational PD-1 immune checkpoint inhibitor, and Yervoy given either concurrently or sequentially in patients with advanced melanoma. After an additional year of follow up of the cohort that received the concurrent combination regimen of nivolumab 1 mg/kg plus Yervoy 3mg/kg, the one-year overall survival rate was 94% and the two-year OS rate was 88%. These are the doses used in the ongoing Phase 2 and Phase 3 trials, CheckMate -069 and -067. No new safety signals were reported in the concurrent combination cohorts with additional follow up and grade 3-4 treatment-related adverse events occurred in 62% of patients. The most common were asymptomatic increases in lipase, ALT and AST. These data will be presented today at the 50th Annual Meeting of the American Society of Clinical Oncology and featured during an ASCO press briefing at 8 a.m. CDT.
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August 21, 2014
13:32 EDTBMYBristol-Myers, Pfizer announce approval of Eliquis for treatment of DVT, PE
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August 20, 2014
08:03 EDTBMYBristol-Myers Pfizer to present new Eliquis data
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08:02 EDTBMYBristol-Myers, Celgene enter collaboration agreement for OPDIVO, ABRAXANE
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August 18, 2014
07:57 EDTBMYCambridge Healthtech Institute to hold a summit
6th Annual Bioprocessing Summit to be held in Boston on August 18-22.
August 8, 2014
10:03 EDTBMYBristol-Myers Hodgkin lymphoma treatment granted orphan drug status
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August 7, 2014
11:02 EDTBMYBristol-Myers enters development pact with Leica Biosystem
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