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March 24, 2014
06:30 EDTBCLIBrainStorm Cell granted U.S. patent for autologous stem cell technology
BrainStorm Cell Therapeutics announced that the U.S. Patent and Trademark Office has granted the company a key patent for its autologous stem cell technology. The patent covers BrainStorm's proprietary stem cells induced to secrete elevated levels of neurotrophic factors for the treatment of neurodegenerative diseases. The neurotrophic factors secreted by the company's patented cells include Glial Cell-Derived Neurotrophic Factor, or GDNF, and Brain-Derived Neurotrophic Factor, or BDNF, known to support the neural cell network by protection of existing motor neurons, promotion of motor neuron growth, and re-establishment of nerve-muscle interaction. The level of secretion of these factors is several-fold higher in BrainStorm's patented cells than in non-induced mesenchymal stem cells. Pending approval from the FDA, the company is currently preparing for its upcoming multi-center Phase II trial in the U.S. with its proprietary NurOwn stem cell therapy, which was developed with these cells.
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