Antares Pharma announces presentation of poster on VIBEX injector Antares Pharma announced the presentation of a scientific poster at the 16th International Congress of Endocrinology and the Endocrine Society’s 96th Annual Meeting & Expo held in Chicago, Illinois. The poster presents the final pharmacokinetic and safety results from 29 randomized patients treated with a once-weekly injection of testosterone administered subcutaneously with the company’s VIBEX QuickShot auto injector. The company’s previously reported interim results from this multi-center phase 2 clinical study were also presented as a scientific abstract at the same meeting. Results from 29 adult males ages 31 to 69 with hypogonadism symptoms and screening testosterone blood levels less than 300 ng/dl were reported. These patients were randomized into two groups and followed for 10 weeks. The first group received weekly 50 mg testosterone administered subcutaneously with a novel auto injector, and the second group received 100 mg of testosterone using the same device and time sequence. The mean testosterone baseline was 244 ng/dL in the 50 mg group and 243.7ng/dL in the 100 mg group. Testosterone levels normalized within hours of the first dose. At week six of the study when patients were at steady state pharmacokinetic conditions, the 50 mg and 100 mg groups had average plasma testosterone values within the normal range at 422ng/dL and 896 ng/dL, respectively. Rapid restoration, consistent maintenance of normal testosterone levels and dose proportionality of the 50 mg and 100 mg strengths were thereby demonstrated. The once-weekly, virtually pain-free administration took three to four seconds and consistently provided a precise dose of 0.5 ml.