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February 28, 2013
07:15 EDTARWRArrowHead Research receives notice of patent allowance
Arrowhead Research Corporation announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for U.S. Patent Application Number 13/336,028 entitled, “In Vivo Polynucleotide Delivery Conjugates Having Enzyme Sensitive Linkages.” The company has previously reported target gene knockdown of 99% in monkeys after a single subcutaneous injection of 1 mg/kg, with >80% knockdown for 3 months. Additional data will be reported at upcoming scientific conferences and through peer-reviewed publications, the company said.
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May 13, 2013
16:39 EDTARWRSabby reports 6.99% passive stake in ArrowHead Research
May 9, 2013
17:19 EDTARWRRA Capital reports 9.9% passive stake in ArrowHead Research
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16:45 EDTARWRCamber Capital reports 9.9% passive stake in ArrowHead Research
May 7, 2013
07:31 EDTARWRArrowHead Research receives notice of allowance from USPTO
Arrowhead Research announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office, or USPTO, for U.S. Patent Application Number 13/326,433 entitled, " Peptide-Based In Vivo siRNA Delivery System." The allowed claims specifically protect the use of targeted melittin or melittin-like peptides to facilitate delivery of siRNA conjugates to hepatocytes. This new patent protection covers the composition of the Dynamic Polyconjugate, or DPC, delivery system used in Arrowhead's RNAi-based drug candidate, ARC-520, against chronic hepatitis B virus infection.

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