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News Breaks
November 27, 2012
07:08 EDTARWRArrowHead Research publishes results regarding company's Dynamic Polyconjugate
Arrowhead Research announced the publication of data demonstrating that high level target gene knockdown with low doses of cholesterol-siRNA is possible in non-human primates using the company's Dynamic Polyconjugate delivery system and a novel co-injection strategy. This new delivery approach dramatically increases the efficacy of cholesterol-siRNA and, together with the co-injection strategy, simplifies the manufacturing process to enable a commercially scalable delivery vehicle for RNAi therapeutics. The company is using this strategy and a next generation DPC polymer in ARC-520, its hepatitis B clinical candidate. The paper titled, "Co-injection of a targeted, reversibly masked endosomolytic polymer dramatically improves the efficacy of cholesterol-conjugated siRNAs in vivo," was published online ahead of print in the journal Nucleic Acid Therapeutics to be featured in the December issue
News For ARWR From The Last 14 Days
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October 23, 2014
07:44 EDTARWRArrowhead management to meet with Deutsche Bank
Meetings to be held in Minneapolis/Chicago on October 23 hosted by Deutsche Bank.
October 15, 2014
09:57 EDTARWRLeerink biotech analysts hold an analyst/industry conference call
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06:06 EDTARWRArrowhead pullback since ARC-520 data an overreaction, says Piper Jaffray
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October 14, 2014
14:54 EDTARWRQVT Financial raises passive stake in Arrowhead to 7.62% from 5.29%
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October 13, 2014
07:12 EDTARWROligonucleotide Therapeutics Society to hold annual meeting
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October 10, 2014
12:11 EDTARWROptions with increasing implied volatility
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